Magnetic resonance imaging of hyperpolarized 3He Detected With a High-Tc SQUID in microtesla magnetic field at laboratory environment fields

Hsin Hsien Chen; Hong Chang Yang; Herng Er Horng; S. H. Liao; Shieh Yueh Yang; K. L. Chen; L. M. Wang; M. J. Chen

doi:10.1109/TASC.2010.2084057

Magnetic resonance imaging of hyperpolarized ³He Detected With a High-T_c SQUID in microtesla magnetic field at laboratory environment fields

Hsin Hsien Chen^*, Hong Chang Yang, Herng Er Horng, S. H. Liao, Shieh Yueh Yang, K. L. Chen, L. M. Wang, M. J. Chen

^*此作品的通信作者

光電工程學士學位學程

研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

4 引文斯高帕斯（Scopus）

摘要

Nuclear magnetic resonance and imaging (NMR/MRI) of optically pumped (OP) hyperpolarized ³He were studied by using a high-_c SQUID magnetometer device in microtesla magnetic fields. The OP cell was filled with a few milligrams of Rb metal, 0.0798 bar N₂ gas and 0.705 bar ³He gas. The ³He cell had been hyperpolarized at an optical pumping system for 5 ∼ hours first; then it was moved to the SQUID-detected nuclear magnetic resonance and imaging system to measure. An appropriate B₁ pulse level and time duration generated a 5° low flip angle of polarization. The free induction decay NMR signals were measured. The spin-lattice relaxation time (T₁) of ³He was 4.7 hours.We improved the line width of NMR spectrum to 0.8 Hz by compensating the inhomogeneous gradient field of environment. The filtered back projection image of hyperpolarized ³He could show a clear image in one shot. The SQUID-detected NMR/MRI would be a great interest for biological imaging.

原文	英語
文章編號	5621847
頁（從 - 到）	505-508
頁數	4
期刊	IEEE Transactions on Applied Superconductivity
卷	21
發行號	3 PART 1
DOIs	https://doi.org/10.1109/TASC.2010.2084057
出版狀態	已發佈 - 2011 6月

ASJC Scopus subject areas

電子、光磁材料
凝聚態物理學
電氣與電子工程

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10.1109/TASC.2010.2084057

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引用此

Chen, H. H., Yang, H. C., Horng, H. E., Liao, S. H., Yang, S. Y., Chen, K. L., Wang, L. M., & Chen, M. J. (2011). Magnetic resonance imaging of hyperpolarized ³He Detected With a High-T_c SQUID in microtesla magnetic field at laboratory environment fields. IEEE Transactions on Applied Superconductivity, 21(3 PART 1), 505-508. 文章 5621847. https://doi.org/10.1109/TASC.2010.2084057

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title = "Magnetic resonance imaging of hyperpolarized 3He Detected With a High-Tc SQUID in microtesla magnetic field at laboratory environment fields",

abstract = "Nuclear magnetic resonance and imaging (NMR/MRI) of optically pumped (OP) hyperpolarized 3He were studied by using a high-c SQUID magnetometer device in microtesla magnetic fields. The OP cell was filled with a few milligrams of Rb metal, 0.0798 bar N2 gas and 0.705 bar 3He gas. The 3He cell had been hyperpolarized at an optical pumping system for 5 ∼ hours first; then it was moved to the SQUID-detected nuclear magnetic resonance and imaging system to measure. An appropriate B1 pulse level and time duration generated a 5° low flip angle of polarization. The free induction decay NMR signals were measured. The spin-lattice relaxation time (T1) of 3He was 4.7 hours.We improved the line width of NMR spectrum to 0.8 Hz by compensating the inhomogeneous gradient field of environment. The filtered back projection image of hyperpolarized 3He could show a clear image in one shot. The SQUID-detected NMR/MRI would be a great interest for biological imaging.",

keywords = "Flux coupling, Hyperpolarized gas, NMR/MRI, SQUID",

author = "Chen, {Hsin Hsien} and Yang, {Hong Chang} and Horng, {Herng Er} and Liao, {S. H.} and Yang, {Shieh Yueh} and Chen, {K. L.} and Wang, {L. M.} and Chen, {M. J.}",

note = "Funding Information: Manuscript received August 02, 2010; accepted September 28, 2010. Date of publication November 09, 2010; date of current version May 27, 2011. This work is supported by the National Science Council of Taiwan under grant no. 98-2752-M-002-003-PAE.",

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doi = "10.1109/TASC.2010.2084057",

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AU - Yang, Hong Chang

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AU - Liao, S. H.

AU - Yang, Shieh Yueh

AU - Chen, K. L.

AU - Wang, L. M.

AU - Chen, M. J.

N1 - Funding Information: Manuscript received August 02, 2010; accepted September 28, 2010. Date of publication November 09, 2010; date of current version May 27, 2011. This work is supported by the National Science Council of Taiwan under grant no. 98-2752-M-002-003-PAE.

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N2 - Nuclear magnetic resonance and imaging (NMR/MRI) of optically pumped (OP) hyperpolarized 3He were studied by using a high-c SQUID magnetometer device in microtesla magnetic fields. The OP cell was filled with a few milligrams of Rb metal, 0.0798 bar N2 gas and 0.705 bar 3He gas. The 3He cell had been hyperpolarized at an optical pumping system for 5 ∼ hours first; then it was moved to the SQUID-detected nuclear magnetic resonance and imaging system to measure. An appropriate B1 pulse level and time duration generated a 5° low flip angle of polarization. The free induction decay NMR signals were measured. The spin-lattice relaxation time (T1) of 3He was 4.7 hours.We improved the line width of NMR spectrum to 0.8 Hz by compensating the inhomogeneous gradient field of environment. The filtered back projection image of hyperpolarized 3He could show a clear image in one shot. The SQUID-detected NMR/MRI would be a great interest for biological imaging.

AB - Nuclear magnetic resonance and imaging (NMR/MRI) of optically pumped (OP) hyperpolarized 3He were studied by using a high-c SQUID magnetometer device in microtesla magnetic fields. The OP cell was filled with a few milligrams of Rb metal, 0.0798 bar N2 gas and 0.705 bar 3He gas. The 3He cell had been hyperpolarized at an optical pumping system for 5 ∼ hours first; then it was moved to the SQUID-detected nuclear magnetic resonance and imaging system to measure. An appropriate B1 pulse level and time duration generated a 5° low flip angle of polarization. The free induction decay NMR signals were measured. The spin-lattice relaxation time (T1) of 3He was 4.7 hours.We improved the line width of NMR spectrum to 0.8 Hz by compensating the inhomogeneous gradient field of environment. The filtered back projection image of hyperpolarized 3He could show a clear image in one shot. The SQUID-detected NMR/MRI would be a great interest for biological imaging.

KW - Flux coupling

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Magnetic resonance imaging of hyperpolarized 3He Detected With a High-Tc SQUID in microtesla magnetic field at laboratory environment fields

摘要

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Magnetic resonance imaging of hyperpolarized ³He Detected With a High-T_c SQUID in microtesla magnetic field at laboratory environment fields