Magnetic relaxation measurement in immunoassay using high-transition- temperature superconducting quantum interference device system

Hong-Chang Yang*, Shieh-Yueh Yang, G. L. Fang, W. H. Huang, C. H. Liu, S. H. Liao, Herng-Er Horng, Chin Yih Hong

*此作品的通信作者

研究成果: 雜誌貢獻期刊論文同行評審

27 引文 斯高帕斯(Scopus)

摘要

Due to their ultrahigh sensitivity to magnetic flux, superconducting quantum interference devices (SQUIDs) are able to detect biomagnetic signals. By labeling biotargets with magnetic nanoparticles, several groups have shown that SQUIDs are promising as quantitative probes of biotargets by measuring their magnetic properties. In this work, we describe the design and construction of a high-transition-temperature radio-frequency SQUID magnetometer system for measuring the magnetic relaxation of labeled avidin. We also describe the synthesis of magnetic nanoparticles coated with biotin for use in labeling the avidin. Furthermore, the specifications of the SQUID-based magnetically labeled immunoassay of avidin are explored.

原文英語
文章編號124701
期刊Journal of Applied Physics
99
發行號12
DOIs
出版狀態已發佈 - 2006

ASJC Scopus subject areas

  • 物理與天文學 (全部)

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