Magnetic nano-particles and their applications in immunoassays

H. E. Horng, S. Y. Yang, Chin Yih Hong, H. C. Yang, S. H. Liao, C. M. Liu, C. C. Wu

    研究成果: 雜誌貢獻文章

    9 引文 斯高帕斯(Scopus)


    Biocompatible magnetic nano-particles show great potential in bio-magnetic applications, such as MRI contrast agents, drug delivery, magnetically labeled immunoassays, and so on. In this work, the feasibility of magnetically labeled immunoassay using bio-compatible magnetic nano-particles is investigated. To do this, we study the synthesis technologies for magnetic nano-particles of Fe 3O4, as well as the coating of various bio-probes onto the magnetic nano-particles to detect the bio-targets avidin, such as, etc. Furthermore, different measurements, like magnetic relaxation and saturated magnetization, for the amounts of bio-targets are developed. In order to achieve an ultra-high sensitivity in magnetically labeled immunoassays, we used SQUIDs because SQUIDs are the most sensitive sensors for magnetic signals. The characterizations of these magnetically labeled immunological measurements are discussed.

    頁(從 - 到)999-1003
    期刊Journal of the Korean Physical Society
    發行號5 I
    出版狀態已發佈 - 2006 五月 1


    ASJC Scopus subject areas

    • Physics and Astronomy(all)


    Horng, H. E., Yang, S. Y., Hong, C. Y., Yang, H. C., Liao, S. H., Liu, C. M., & Wu, C. C. (2006). Magnetic nano-particles and their applications in immunoassays. Journal of the Korean Physical Society, 48(5 I), 999-1003.