Magnetic nano-particles and their applications in immunoassays

H. E. Horng, S. Y. Yang, Chin Yih Hong, H. C. Yang, S. H. Liao, C. M. Liu, C. C. Wu

    研究成果: 雜誌貢獻文章

    9 引文 斯高帕斯(Scopus)

    摘要

    Biocompatible magnetic nano-particles show great potential in bio-magnetic applications, such as MRI contrast agents, drug delivery, magnetically labeled immunoassays, and so on. In this work, the feasibility of magnetically labeled immunoassay using bio-compatible magnetic nano-particles is investigated. To do this, we study the synthesis technologies for magnetic nano-particles of Fe 3O4, as well as the coating of various bio-probes onto the magnetic nano-particles to detect the bio-targets avidin, such as, etc. Furthermore, different measurements, like magnetic relaxation and saturated magnetization, for the amounts of bio-targets are developed. In order to achieve an ultra-high sensitivity in magnetically labeled immunoassays, we used SQUIDs because SQUIDs are the most sensitive sensors for magnetic signals. The characterizations of these magnetically labeled immunological measurements are discussed.

    原文英語
    頁(從 - 到)999-1003
    頁數5
    期刊Journal of the Korean Physical Society
    48
    發行號5 I
    出版狀態已發佈 - 2006 五月 1

      指紋

    ASJC Scopus subject areas

    • Physics and Astronomy(all)

    引用此

    Horng, H. E., Yang, S. Y., Hong, C. Y., Yang, H. C., Liao, S. H., Liu, C. M., & Wu, C. C. (2006). Magnetic nano-particles and their applications in immunoassays. Journal of the Korean Physical Society, 48(5 I), 999-1003.