Low-Field nuclear magnetic resonance and magnetic resonance imaging using a high-tc squid for tumor detection

Kai Wen Huang; Shu Hsien Liao; Hong Chang Yang; Hsin Hsien Chen; Herng Er Horng; M. J. Chen; Shieh Yueh Yang

doi:10.1109/TASC.2010.2083617

Low-Field nuclear magnetic resonance and magnetic resonance imaging using a high-tc squid for tumor detection

Kai Wen Huang^*, Shu Hsien Liao, Hong Chang Yang, Hsin Hsien Chen, Herng Er Horng, M. J. Chen, Shieh Yueh Yang

^*此作品的通信作者

研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

4 引文斯高帕斯（Scopus）

摘要

In this work, a study of hepatocellular carcinoma and normal livers in rats using nuclear magnetic resonance (NMR) based on superconducting quantum interference devices (SQUIDs) was presented. The time domain free induction decay signals,S_y(t) of cancerous liver tissue and control liver tissue of rats were measured to study the respective longitudinal relaxation rate T¹₁ The NMR data were fitted to [T-exp(-T _Bp/T₁ to derive the longitudinal relaxation times T ₁ for cancerous liver tissue and control liver tissue. It is found that T₁ cancer of cancerous liver tissues is 2.3 times higher than T₁ control of control liver tissues. Statistically the data suggest that T_1cancer T₁ control can be used to discriminate cancerous liver tissue from control tissue. Furthermore, differentiating cancerous tissues from control tissues was demonstrated using magnetic fluid phantoms as phantoms for cancerous and control tissues. The SQUID-detected NMR/MRI exhibits potential applications in clinical research.

原文	英語
文章編號	5621873
頁（從 - 到）	461-464
頁數	4
期刊	IEEE Transactions on Applied Superconductivity
卷	21
發行號	3 PART 1
DOIs	https://doi.org/10.1109/TASC.2010.2083617
出版狀態	已發佈 - 2011 6月
對外發佈	是

ASJC Scopus subject areas

電子、光磁材料
凝聚態物理學
電氣與電子工程

UN SDG

此研究成果有助於以下永續發展目標

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10.1109/TASC.2010.2083617

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Low-Field nuclear magnetic resonance and magnetic resonance imaging using a high-tc squid for tumor detection. / Huang, Kai Wen; Liao, Shu Hsien; Yang, Hong Chang; Chen, Hsin Hsien; Horng, Herng Er; Chen, M. J.; Yang, Shieh Yueh.

於: IEEE Transactions on Applied Superconductivity, 卷 21, 編號 3 PART 1, 5621873, 06.2011, p. 461-464.

研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

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title = "Low-Field nuclear magnetic resonance and magnetic resonance imaging using a high-tc squid for tumor detection",

abstract = "In this work, a study of hepatocellular carcinoma and normal livers in rats using nuclear magnetic resonance (NMR) based on superconducting quantum interference devices (SQUIDs) was presented. The time domain free induction decay signals,Sy(t) of cancerous liver tissue and control liver tissue of rats were measured to study the respective longitudinal relaxation rate T11 The NMR data were fitted to [T-exp(-T Bp/T1 to derive the longitudinal relaxation times T 1 for cancerous liver tissue and control liver tissue. It is found that T1 cancer of cancerous liver tissues is 2.3 times higher than T1 control of control liver tissues. Statistically the data suggest that T1cancer T1 control can be used to discriminate cancerous liver tissue from control tissue. Furthermore, differentiating cancerous tissues from control tissues was demonstrated using magnetic fluid phantoms as phantoms for cancerous and control tissues. The SQUID-detected NMR/MRI exhibits potential applications in clinical research.",

keywords = "Flux coupling, Hepatocellular carcinoma (HCC), Nmr, SQUID",

author = "Huang, {Kai Wen} and Liao, {Shu Hsien} and Yang, {Hong Chang} and Chen, {Hsin Hsien} and Horng, {Herng Er} and Chen, {M. J.} and Yang, {Shieh Yueh}",

note = "Funding Information: Manuscript received August 03, 2010; accepted September 26, 2010. Date of publication November 09, 2010; date of current version May 27, 2011. This work was supported by the National Science Council of Taiwan under Grant 98-2752-M-002-003-PAE.",

year = "2011",

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doi = "10.1109/TASC.2010.2083617",

language = "English",

volume = "21",

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AU - Horng, Herng Er

AU - Chen, M. J.

AU - Yang, Shieh Yueh

N1 - Funding Information: Manuscript received August 03, 2010; accepted September 26, 2010. Date of publication November 09, 2010; date of current version May 27, 2011. This work was supported by the National Science Council of Taiwan under Grant 98-2752-M-002-003-PAE.

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N2 - In this work, a study of hepatocellular carcinoma and normal livers in rats using nuclear magnetic resonance (NMR) based on superconducting quantum interference devices (SQUIDs) was presented. The time domain free induction decay signals,Sy(t) of cancerous liver tissue and control liver tissue of rats were measured to study the respective longitudinal relaxation rate T11 The NMR data were fitted to [T-exp(-T Bp/T1 to derive the longitudinal relaxation times T 1 for cancerous liver tissue and control liver tissue. It is found that T1 cancer of cancerous liver tissues is 2.3 times higher than T1 control of control liver tissues. Statistically the data suggest that T1cancer T1 control can be used to discriminate cancerous liver tissue from control tissue. Furthermore, differentiating cancerous tissues from control tissues was demonstrated using magnetic fluid phantoms as phantoms for cancerous and control tissues. The SQUID-detected NMR/MRI exhibits potential applications in clinical research.

AB - In this work, a study of hepatocellular carcinoma and normal livers in rats using nuclear magnetic resonance (NMR) based on superconducting quantum interference devices (SQUIDs) was presented. The time domain free induction decay signals,Sy(t) of cancerous liver tissue and control liver tissue of rats were measured to study the respective longitudinal relaxation rate T11 The NMR data were fitted to [T-exp(-T Bp/T1 to derive the longitudinal relaxation times T 1 for cancerous liver tissue and control liver tissue. It is found that T1 cancer of cancerous liver tissues is 2.3 times higher than T1 control of control liver tissues. Statistically the data suggest that T1cancer T1 control can be used to discriminate cancerous liver tissue from control tissue. Furthermore, differentiating cancerous tissues from control tissues was demonstrated using magnetic fluid phantoms as phantoms for cancerous and control tissues. The SQUID-detected NMR/MRI exhibits potential applications in clinical research.

KW - Flux coupling

KW - Hepatocellular carcinoma (HCC)

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KW - SQUID

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Low-Field nuclear magnetic resonance and magnetic resonance imaging using a high-tc squid for tumor detection

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UN SDG

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