摘要
The iodine-catalyzed cascade reaction of ortho-formylarylketones with indoles for the synthesis of indolylbenzo[b]carbazoles is reported. The reaction is initiated in the presence of iodine by two successive nucleophilic additions of indoles with an aldehyde group of ortho-formylarylketones, and the ketone does not undergo a nucleophilic addition and only involves in the Friedel-Crafts-type cyclization. A variety of substrates are tested, and the efficiency of this reaction is demonstrated with gram-scale reactions.
| 原文 | 英語 |
|---|---|
| 頁（從 - 到） | 3666-3677 |
| 頁數 | 12 |
| 期刊 | Journal of Organic Chemistry |
| 卷 | 88 |
| 發行號 | 6 |
| DOIs | |
| 出版狀態 | 已發佈 - 2023 3月 17 |
ASJC Scopus subject areas
- 有機化學
指紋
深入研究「Iodine-Catalyzed Annulation Reaction of Ortho-Formylarylketones with Indoles: A General Strategy for the Synthesis of Indolylbenzo[b]carbazoles」主題。共同形成了獨特的指紋。資料集
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CCDC 2221781: Experimental Crystal Structure Determination
Suresh, S. (Contributor), Kavala, V. (Contributor) & Yao, C. (Contributor), Cambridge Crystallographic Data Centre, 2023
DOI: 10.5517/ccdc.csd.cc2dkyc9, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc2dkyc9&sid=DataCite
資料集: Dataset
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CCDC 2221782: Experimental Crystal Structure Determination
Suresh, S. (Contributor), Kavala, V. (Contributor) & Yao, C. (Contributor), Cambridge Crystallographic Data Centre, 2023
DOI: 10.5517/ccdc.csd.cc2dkydb, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc2dkydb&sid=DataCite
資料集: Dataset
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CCDC 2221783: Experimental Crystal Structure Determination
Suresh, S. (Contributor), Kavala, V. (Contributor) & Yao, C. (Contributor), Cambridge Crystallographic Data Centre, 2023
DOI: 10.5517/ccdc.csd.cc2dkyfc, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc2dkyfc&sid=DataCite
資料集: Dataset