Indoor ozone and particulate matter modify the association between airborne endotoxin and schoolchildren's lung function

Yu Chuan Yen, Chun Yuh Yang, Chi Kung Ho, Pei Chun Yen, Yu Ting Cheng, Kristina D. Mena, Tzu Chi Lee, Pei Shih Chen*

*此作品的通信作者

研究成果: 雜誌貢獻期刊論文同行評審

10 引文 斯高帕斯(Scopus)

摘要

Background: To date, the effect of household airborne pollutants on the association between airborne endotoxin and lung function of schoolchildren is unknown. Objectives: The objective of this study is to evaluate whether indoor air pollutants such as carbon monoxide (CO), carbon dioxide (CO2), nitrogen dioxide (NO2), sulfur dioxide (SO2), ozone (O3), particulate matter with aerodynamic diameter <10 and 2.5 μm (PM10, PM2.5) can modify the association between airborne endotoxin and school children's lung function in a heavy industrial city in Taiwan. Methods: We recruited 120 elementary school-age children in Kaohsiung City, Taiwan. Aerosol samples were collected on a filter membrane for 24 h period and then analyzed for endotoxin. Air pollutants were measured for 24 h in living rooms while school children's lung function was measured. The modification of air pollutants on the relationship between airborne endotoxin and children's lung function was estimated after adjusting the gender, age, height, weight, and case-control status. Results: We found that both O3 and PM10 concentrations significantly modified the relationships between airborne endotoxin and school children's lung function. Among children living in homes with O3 ≥ 0.01 ppm or PM10 ≥ 62 μg/m3, airborne endotoxin was negatively associated with lung functions, whereas among those living in homes with O3 < 0.01 ppm or PM10 < 62 μg/m3, airborne endotoxin was positively associated with lung functions. Conclusions: The indoor air pollutant concentration of O3 and PM10 modifies the association between airborne endotoxin and school children's lung function.

原文英語
文章編號135810
期刊Science of the Total Environment
705
DOIs
出版狀態已發佈 - 2020 2月 25

ASJC Scopus subject areas

  • 環境工程
  • 環境化學
  • 廢物管理和處置
  • 污染

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