Independency of Fe ions in hemoglobin on immunomagnetic reduction assay

S. Y. Yang, C. B. Lan, C. H. Chen, H. E. Horng*, Chin Yih Hong, H. C. Yang, Y. K. Lai, Y. H. Lin, K. S. Teng


研究成果: 雜誌貢獻期刊論文同行評審

4 引文 斯高帕斯(Scopus)


Immunomagnetic reduction (IMR), which involves measuring the reduction in the ac magnetic susceptibility of magnetic reagents, is due to the association between bio-functionalized magnetic nanoparticles and target bio-molecules. This has been demonstrated for assaying proteins in solutions free of Fe ions, such as serum. In this work, the validity of IMR assay for samples rich in Fe ions like hemoglobin (Hb) is investigated. According to the results, there is no magnetic signal contributed by Fe-ion-rich Hb. Furthermore, the results show a high sensitivity in assaying hemoglobin A1c (HbA1c) by using IMR.

頁(從 - 到)3266-3269
期刊Journal of Magnetism and Magnetic Materials
出版狀態已發佈 - 2009 10月

ASJC Scopus subject areas

  • 電子、光磁材料
  • 凝聚態物理學


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