Imaging of Magnetic Nanoparticles Using a Second Harmonic of Magnetization With DC Bias Field

Saburo Tanaka, Hayaki Murata, Tomoya Oishi, Yoshimi Hatsukade, Yi Zhang, Herng Er Horng, Shu Hsien Liao, Hong Chang Yang

    研究成果: 雜誌貢獻期刊論文同行評審

    22 引文 斯高帕斯(Scopus)


    We have developed a method to improve the detection sensitivity for the magnetization M of magnetic nanoparticles (MNPs) using a high Tc superconducting quantum interference device magnetometer. The M response of MNP to an applied magnetic field H(M-H characteristics) can be divided into a linear region and a saturation region, which are separated at a transition point Hk. When applying an excitation ac magnetic field (Hac) and an additional dc bias field Hdc = Hk, the second harmonic of M reaches a maximum due to the nonlinearity of its M - H characteristics. This harmonic is stronger than any other harmonics, including a third harmonic. The advantage of using the second harmonic response is that the response can be measured even in a small field Hac. The M response of MNP was systematically analyzed and experimentally demonstrated. For conventional detection using a third harmonic, the amplitude of the Hac must be larger than the threshold level, which is almost the same as Hk. Detection methods using a second harmonic can be applied to magnetic particle imaging. We finally demonstrate the construction of a 1-D image of two separated bottle-shaped MNP samples using the method with a lock-in amplifier.

    期刊IEEE Transactions on Magnetics
    出版狀態已發佈 - 2015 二月 1

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Electrical and Electronic Engineering

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