Household airborne endotoxin associated with asthma and allergy in elementary school-age children: a case–control study in Kaohsiung, Taiwan

Yu Chuan Yen, Chun Yuh Yang, Tsu Nai Wang, Pei Chun Yen, Chi Kung Ho, Kristina D. Mena, Tzu Chi Lee, Kang Shin Chen, Yuan Chung Lin, Pei Shih Chen*

*此作品的通信作者

研究成果: 雜誌貢獻期刊論文同行評審

4 引文 斯高帕斯(Scopus)

摘要

To evaluate the association between the presence of asthma and allergy, and airborne endotoxin in homes of school-age children in Kaohsiung City, Taiwan, with a case–control study design by matching the age and class exposure. Data collection of home visits included an interviewer-administered questionnaire and air sampling of participants’ homes for endotoxin, bacteria, and fungi, as well as temperature and relative humidity measurements. Endotoxin was detected in all air samples with a median value of 0.67 EU m−3. In the adjusted logistic regression model, household airborne endotoxin was associated with higher prevalence of asthma and allergy; OR = 4.88 (95% CI 1.16–20.55) for Q3 (between 0.67 and 1.97 EU m −3) vs. Q1 (< 0.31 EU m −3), with statistical significance. Airborne fungi were associated with higher prevalence of asthma and allergy; OR = 4.47 (95% CI 1.13–17.69) for Q3 (between 314 and 699 CFU m −3) vs. Q1 (< 159 CFU m −3) in adjusted logistic regression models. Airborne endotoxin and fungi were significantly associated with children’s asthma and allergy.

原文英語
頁(從 - 到)19502-19509
頁數8
期刊Environmental Science and Pollution Research
27
發行號16
DOIs
出版狀態已發佈 - 2020 6月 1

ASJC Scopus subject areas

  • 環境化學
  • 污染
  • 健康、毒理學和誘變

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