Holographic tomography: techniques and biomedical applications [Invited

Vinoth Balasubramani, Arkadiusz Kuś, Han Yen Tu, Chau Jern Cheng, Maria Baczewska, Wojciech Krauze, Małgorzata Kujawińska

研究成果: 雜誌貢獻期刊論文同行評審

摘要

Holographic tomography (HT) is an advanced label-free optical microscopic imaging method used for biological studies. HT uses digital holographic microscopy to record the complex amplitudes of a biological sample as digital holograms and then numerically reconstruct the sample's refractive index (RI) distribution in three dimensions. The RI values are a key parameter for label-free bio-examination, which correlate with metabolic activities and spatiotemporal distribution of biophysical parameters of cells and their internal organelles, tissues, and small-scale biological objects. This article provides insight on this rapidly growing HT field of research and its applications in biology. We present a review summary of the HT principle and highlight recent technical advancement in HT and its applications.

原文英語
頁(從 - 到)B65-B80
期刊Applied Optics
60
發行號10
DOIs
出版狀態已發佈 - 2021 四月 1

ASJC Scopus subject areas

  • 原子與分子物理與光學
  • 工程(雜項)
  • 電氣與電子工程

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