Highly functionalized benzene syntheses by directed mono or multiple magnesiations with TMPMgCl·LiCl

Wenwei Lin; Oliver Baron; Paul Knochel

doi:10.1021/ol0625536

Highly functionalized benzene syntheses by directed mono or multiple magnesiations with TMPMgCl·LiCl

Wenwei Lin
, Oliver Baron
, Paul Knochel^*

^*此作品的通信作者

研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

151 引文斯高帕斯（Scopus）

摘要

The direct magnesiation of highly functionalized aromatics bearing an ester, a nitrile, or a ketone can be readily performed by using an OBoc as a directing group and TMPMgCl·LiCl as a base. It allows, for example, the preparation of a meta-magnesiated benzophenone in >95%. After quenching, highly functionalized and substituted benzenes are obtained.

原文	英語
頁（從 - 到）	5673-5676
頁數	4
期刊	Organic Letters
卷	8
發行號	24
DOIs	https://doi.org/10.1021/ol0625536
出版狀態	已發佈 - 2006 11月 23
對外發佈	是

ASJC Scopus subject areas

生物化學
物理與理論化學
有機化學

存取文件

10.1021/ol0625536

其它文件與鏈接

引用此

@article{3a9c6028fc484607b617fcacdee4512c,

title = "Highly functionalized benzene syntheses by directed mono or multiple magnesiations with TMPMgCl·LiCl",

abstract = "The direct magnesiation of highly functionalized aromatics bearing an ester, a nitrile, or a ketone can be readily performed by using an OBoc as a directing group and TMPMgCl·LiCl as a base. It allows, for example, the preparation of a meta-magnesiated benzophenone in >95\%. After quenching, highly functionalized and substituted benzenes are obtained.",

author = "Wenwei Lin and Oliver Baron and Paul Knochel",

year = "2006",

month = nov,

day = "23",

doi = "10.1021/ol0625536",

language = "English",

volume = "8",

pages = "5673--5676",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "24",

}

TY - JOUR

T1 - Highly functionalized benzene syntheses by directed mono or multiple magnesiations with TMPMgCl·LiCl

AU - Lin, Wenwei

AU - Baron, Oliver

AU - Knochel, Paul

PY - 2006/11/23

Y1 - 2006/11/23

N2 - The direct magnesiation of highly functionalized aromatics bearing an ester, a nitrile, or a ketone can be readily performed by using an OBoc as a directing group and TMPMgCl·LiCl as a base. It allows, for example, the preparation of a meta-magnesiated benzophenone in >95%. After quenching, highly functionalized and substituted benzenes are obtained.

AB - The direct magnesiation of highly functionalized aromatics bearing an ester, a nitrile, or a ketone can be readily performed by using an OBoc as a directing group and TMPMgCl·LiCl as a base. It allows, for example, the preparation of a meta-magnesiated benzophenone in >95%. After quenching, highly functionalized and substituted benzenes are obtained.

UR - https://www.scopus.com/pages/publications/33846031566

UR - https://www.scopus.com/pages/publications/33846031566#tab=citedBy

U2 - 10.1021/ol0625536

DO - 10.1021/ol0625536

M3 - Article

C2 - 17107100

AN - SCOPUS:33846031566

SN - 1523-7060

VL - 8

SP - 5673

EP - 5676

JO - Organic Letters

JF - Organic Letters

IS - 24

ER -

Highly functionalized benzene syntheses by directed mono or multiple magnesiations with TMPMgCl·LiCl

摘要

ASJC Scopus subject areas

存取文件

其它文件與鏈接

指紋

引用此