Highly functionalized benzene syntheses by directed mono or multiple magnesiations with TMPMgCl·LiCl

Wenwei Lin, Oliver Baron, Paul Knochel*

*此作品的通信作者

研究成果: 雜誌貢獻期刊論文同行評審

137 引文 斯高帕斯(Scopus)

摘要

The direct magnesiation of highly functionalized aromatics bearing an ester, a nitrile, or a ketone can be readily performed by using an OBoc as a directing group and TMPMgCl·LiCl as a base. It allows, for example, the preparation of a meta-magnesiated benzophenone in >95%. After quenching, highly functionalized and substituted benzenes are obtained.

原文英語
頁(從 - 到)5673-5676
頁數4
期刊Organic Letters
8
發行號24
DOIs
出版狀態已發佈 - 2006 十一月 23
對外發佈

ASJC Scopus subject areas

  • 生物化學
  • 物理與理論化學
  • 有機化學

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