摘要
The direct magnesiation of highly functionalized aromatics bearing an ester, a nitrile, or a ketone can be readily performed by using an OBoc as a directing group and TMPMgCl·LiCl as a base. It allows, for example, the preparation of a meta-magnesiated benzophenone in >95%. After quenching, highly functionalized and substituted benzenes are obtained.
原文 | 英語 |
---|---|
頁(從 - 到) | 5673-5676 |
頁數 | 4 |
期刊 | Organic Letters |
卷 | 8 |
發行號 | 24 |
DOIs | |
出版狀態 | 已發佈 - 2006 11月 23 |
對外發佈 | 是 |
ASJC Scopus subject areas
- 生物化學
- 物理與理論化學
- 有機化學