摘要
(Chemical Equation Presented) The asymmetric addition of alkenylzincs to aromatic and a-branched aliphatic aldehydes catalyzed by 1 generated the corresponding (E)-allylic alcohols with >95% ee and good to excellent chemical yields, especially >99.5% ee was observed in the case of 4-CF 3-benzaldehyde. Notably, 1 is an effective ligand to catalyze the addition of disubstituted (R2 = R3 = ethyl) and bulky substituted (R2 - H, R3 = tert-butyl) alkenylzincs to benzaldehyde, affording the corresponding allylic alcohols both with 96% ee.
原文 | 英語 |
---|---|
頁(從 - 到) | 5935-5937 |
頁數 | 3 |
期刊 | Journal of Organic Chemistry |
卷 | 72 |
發行號 | 15 |
DOIs | |
出版狀態 | 已發佈 - 2007 7月 20 |
對外發佈 | 是 |
ASJC Scopus subject areas
- 有機化學