Weakly coupled models for the 750 GeV diphoton resonance often invoke new particles carrying both color and/or electric charges to mediate loop-induced couplings of the resonance to two gluons and two photons. The new colored particles may not be stable and could decay into final states containing standard model particles. We consider an electroweak doublet of vectorlike quarks (VLQs) carrying electric charges of 5/3 and 2/3, respectively, which mediate the loop-induced couplings of the 750 GeV resonance. If the VLQ has a mass at around 1 TeV, it naturally gives rise to the observed diphoton signal strength while all couplings remain perturbative up to a high scale. At the same time, if the charge-5/3 VLQ decays into final states containing top quark and W boson, it would contribute to the multilepton excesses observed in both run 1 and run 2 data. It is also possible to incorporate a dark matter candidate in the decay final states to explain the observed relic density.
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