Four-Component Synthesis of Phosphonium Salts: Application Toward an Alternative Approach to Cross-Coupling for the Synthesis of Bis-Heteroarenes

Yi Ru Chen; Ganapuram Madhusudhan Reddy; Shao Hao Hong; Ying Zheng Wang; Jhen Kuei Yu; Wenwei Lin

doi:10.1002/anie.201700945

Four-Component Synthesis of Phosphonium Salts: Application Toward an Alternative Approach to Cross-Coupling for the Synthesis of Bis-Heteroarenes

Yi Ru Chen, Ganapuram Madhusudhan Reddy, Shao Hao Hong, Ying Zheng Wang, Jhen Kuei Yu, Wenwei Lin^*

^*此作品的通信作者

化學系

研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

26 引文斯高帕斯（Scopus）

摘要

A series of stable phosphonium salts have been synthesized via a novel four-component reaction of an arene nucleophile, 2-heteroatom substituted aryl aldehyde, and phosphine in presence of an acid. The phosphonium salts thus obtained were utilized for the synthesis of a variety of bis-heteroarenes, providing an efficient alternative method to the classical cross-coupling strategies.

原文	英語
頁（從 - 到）	5106-5110
頁數	5
期刊	Angewandte Chemie - International Edition
卷	56
發行號	18
DOIs	https://doi.org/10.1002/anie.201700945
出版狀態	已發佈 - 2017 4月 24

ASJC Scopus subject areas

催化
一般化學

存取文件

10.1002/anie.201700945

其它文件與鏈接

CCDC 1527603: Experimental Crystal Structure Determination
Chen, Y. (Creator), Reddy, G. M. (Creator), Hong, S. (Creator), Wang, Y. (Creator), Yu, J. (Creator) & Lin, W. (Creator), Unknown Publisher, 2017
DOI: 10.5517/ccdc.csd.cc1n8lj1, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1n8lj1&sid=DataCite
資料集: Dataset
CCDC 1403386: Experimental Crystal Structure Determination
Chen, Y. (Creator), Reddy, G. M. (Creator), Hong, S. (Creator), Wang, Y. (Creator), Yu, J. (Creator) & Lin, W. (Creator), Unknown Publisher, 2017
DOI: 10.5517/ccdc.csd.cc1j3bjh, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1j3bjh&sid=DataCite
資料集: Dataset
CCDC 1403240: Experimental Crystal Structure Determination
Chen, Y. (Creator), Reddy, G. M. (Creator), Hong, S. (Creator), Wang, Y. (Creator), Yu, J. (Creator) & Lin, W. (Creator), Unknown Publisher, 2017
DOI: 10.5517/ccdc.csd.cc1j35tm, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1j35tm&sid=DataCite
資料集: Dataset

引用此

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abstract = "A series of stable phosphonium salts have been synthesized via a novel four-component reaction of an arene nucleophile, 2-heteroatom substituted aryl aldehyde, and phosphine in presence of an acid. The phosphonium salts thus obtained were utilized for the synthesis of a variety of bis-heteroarenes, providing an efficient alternative method to the classical cross-coupling strategies.",

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note = "Publisher Copyright: {\textcopyright} 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim",

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doi = "10.1002/anie.201700945",

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T1 - Four-Component Synthesis of Phosphonium Salts

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AU - Chen, Yi Ru

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AU - Hong, Shao Hao

AU - Wang, Ying Zheng

AU - Yu, Jhen Kuei

AU - Lin, Wenwei

PY - 2017/4/24

Y1 - 2017/4/24

N2 - A series of stable phosphonium salts have been synthesized via a novel four-component reaction of an arene nucleophile, 2-heteroatom substituted aryl aldehyde, and phosphine in presence of an acid. The phosphonium salts thus obtained were utilized for the synthesis of a variety of bis-heteroarenes, providing an efficient alternative method to the classical cross-coupling strategies.

AB - A series of stable phosphonium salts have been synthesized via a novel four-component reaction of an arene nucleophile, 2-heteroatom substituted aryl aldehyde, and phosphine in presence of an acid. The phosphonium salts thus obtained were utilized for the synthesis of a variety of bis-heteroarenes, providing an efficient alternative method to the classical cross-coupling strategies.

KW - Wittig reactions

KW - bis-heteroarenes

KW - cross-coupling

KW - multicomponent reactions

KW - organophosphonium salts

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JO - Angewandte Chemie - International Edition

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IS - 18

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Four-Component Synthesis of Phosphonium Salts: Application Toward an Alternative Approach to Cross-Coupling for the Synthesis of Bis-Heteroarenes

摘要

ASJC Scopus subject areas

存取文件

其它文件與鏈接

指紋

資料集

CCDC 1527603: Experimental Crystal Structure Determination

CCDC 1403386: Experimental Crystal Structure Determination

CCDC 1403240: Experimental Crystal Structure Determination

引用此