@article{8077706aef194ed2836b5aa06805a7a8,
title = "Formal Alkenylation and Amination of 2-Nitrobenzofurans with Fumaric Acid Amide Ester under Metal-Free Conditions",
abstract = "An inorganic base promoted metal-free formal alkenylation and amination of 2-nitrobenzofurans is established with fumaric acid amide ester derivatives. The cascade strategy provides the 2-alkenyl and 3-amino substituted benzofurans via Michael addition/cyclization/nitrous acid elimination/N-demethoxylation/C−N bond cleavage and isomerization sequence. The desired 2-(3-aminobenzofuran-2-yl)malonate derivatives are obtained in moderate-to-good yields with high stereoselectivity under mild reaction conditions (up to 71 % yield and >20 : 1 Z : E). The structure of the products is assigned from the single crystal x-ray structural analysis.",
keywords = "2-Nitrobenzofuran, Alkenylation, Amination, Furmaric acid amide ester, Nitrous acid elimination",
author = "{Ananda Rao}, Gunda and Paru Jamwal and Ramani Gurubrahamam and Kwunmin Chen",
note = "Funding Information: . We thank the Ministry of Science and Technology of the Republicof China (MOST 109‐2113‐M‐003‐004) for financial support of this work. RG thankful to the SERB grant (SRG/2021/001539) and PJ thankful to the UGC for fellowship Publisher Copyright: {\textcopyright} 2023 Wiley-VCH GmbH.",
year = "2023",
month = jan,
day = "9",
doi = "10.1002/slct.202204467",
language = "English",
volume = "8",
journal = "ChemistrySelect",
issn = "2365-6549",
publisher = "Wiley-Blackwell Publishing Ltd",
number = "1",
}