First-generation hybrid MEMS gas chromatograph

Chia Jung Lu, William H. Steinecker, Wei Cheng Tian, Michael C. Oborny, Jamie M. Nichols, Masoud Agah, Joseph A. Potkay, Helena K.L. Chan, Jeffrey Driscoll, Richard D. Sacks, Kensall D. Wise, Stella W. Pang, Edward T. Zellers

研究成果: 雜誌貢獻文章

198 引文 斯高帕斯(Scopus)

摘要

The fabrication, assembly, and initial testing of a hybrid microfabricated gas Chromatograph (μGC) is described. The μGC incorporates capabilities for on-board calibration, sample preconcentration and focused thermal desorption, temperature-programmed separations, and "spectral" detection with an integrated array of microsensors, and is designed for rapid determinations of complex mixtures of environmental contaminants at trace concentrations. Ambient air is used as the carrier gas to avoid the need for on-board gas supplies. The microsystem is plumbed through an etched-Si/glass microfluidic interconnection substrate with fused silica capillaries and employs a miniature commercial pump and valve subsystem for directing sample flow. The latest performance data on each system component are presented followed by first analytical results from the working microsystem. Tradeoffs in system performance as a function of volumetric flow rate are explored. The determination of an 11-vapor mixture of typical indoor air contaminants in less than 90 s is demonstrated with projected detection limits in the low part-per-billion concentration range for a preconcentrated air-sample volume of 0.25 L.

原文英語
頁(從 - 到)1123-1131
頁數9
期刊Lab on a Chip
5
發行號10
DOIs
出版狀態已發佈 - 2005 十月

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Biomedical Engineering

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    Lu, C. J., Steinecker, W. H., Tian, W. C., Oborny, M. C., Nichols, J. M., Agah, M., Potkay, J. A., Chan, H. K. L., Driscoll, J., Sacks, R. D., Wise, K. D., Pang, S. W., & Zellers, E. T. (2005). First-generation hybrid MEMS gas chromatograph. Lab on a Chip, 5(10), 1123-1131. https://doi.org/10.1039/b508596a