FeCl3 catalyzed regioselective C -alkylation of indolylnitroalkenes with amino group substituted arenes

Manoj R. Zanwar; Veerababurao Kavala; Sachin D. Gawande; Chun Wei Kuo; Wen Chang Huang; Ting Shen Kuo; Hsiu Ni Huang; Chiu Hui He; Ching Fa Yao

doi:10.1021/jo4025368

FeCl₃ catalyzed regioselective C -alkylation of indolylnitroalkenes with amino group substituted arenes

Manoj R. Zanwar, Veerababurao Kavala, Sachin D. Gawande, Chun Wei Kuo, Wen Chang Huang^*, Ting Shen Kuo, Hsiu Ni Huang, Chiu Hui He, Ching Fa Yao

^*此作品的通信作者

化學系

研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

7 引文斯高帕斯（Scopus）

摘要

An efficient FeCl₃ catalyzed protocol for the synthesis of amino functionalized indolylnitroalkanes from easily available precursor indolylnitroalkenes and substituted amines has been developed. Regioselective C-alkylation in the presence of free amino substituted arenes occurred. The scope of this methodology shows good functional group tolerance, and further, this protocol was used to prepare indolylquinoline derivatives.

原文	英語
頁（從 - 到）	1842-1849
頁數	8
期刊	Journal of Organic Chemistry
卷	79
發行號	4
DOIs	https://doi.org/10.1021/jo4025368
出版狀態	已發佈 - 2014 2月 21

ASJC Scopus subject areas

有機化學

存取文件

10.1021/jo4025368

其它文件與鏈接

CCDC 966333: Experimental Crystal Structure Determination
Zanwar, M. R. (Creator), Kavala, V. (Creator), Gawande, S. D. (Creator), Kuo, C. (Creator), Huang, W. (Creator), Kuo, T. (Creator), Huang, H. (Creator), He, C. (Creator) & Yao, C. (Creator), Unknown Publisher, 2014
DOI: 10.5517/cc11fk12, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc11fk12&sid=DataCite
資料集: Dataset
CCDC 966332: Experimental Crystal Structure Determination
Zanwar, M. R. (Creator), Kavala, V. (Creator), Gawande, S. D. (Creator), Kuo, C. (Creator), Huang, W. (Creator), Kuo, T. (Creator), Huang, H. (Creator), He, C. (Creator) & Yao, C. (Creator), Unknown Publisher, 2014
DOI: 10.5517/cc11fk01, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc11fk01&sid=DataCite
資料集: Dataset

引用此

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title = "FeCl3 catalyzed regioselective C -alkylation of indolylnitroalkenes with amino group substituted arenes",

abstract = "An efficient FeCl3 catalyzed protocol for the synthesis of amino functionalized indolylnitroalkanes from easily available precursor indolylnitroalkenes and substituted amines has been developed. Regioselective C-alkylation in the presence of free amino substituted arenes occurred. The scope of this methodology shows good functional group tolerance, and further, this protocol was used to prepare indolylquinoline derivatives.",

author = "Zanwar, {Manoj R.} and Veerababurao Kavala and Gawande, {Sachin D.} and Kuo, {Chun Wei} and Huang, {Wen Chang} and Kuo, {Ting Shen} and Huang, {Hsiu Ni} and He, {Chiu Hui} and Yao, {Ching Fa}",

year = "2014",

month = feb,

day = "21",

doi = "10.1021/jo4025368",

language = "English",

volume = "79",

pages = "1842--1849",

journal = "Journal of Organic Chemistry",

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TY - JOUR

T1 - FeCl3 catalyzed regioselective C -alkylation of indolylnitroalkenes with amino group substituted arenes

AU - Zanwar, Manoj R.

AU - Kavala, Veerababurao

AU - Gawande, Sachin D.

AU - Kuo, Chun Wei

AU - Huang, Wen Chang

AU - Kuo, Ting Shen

AU - Huang, Hsiu Ni

AU - He, Chiu Hui

AU - Yao, Ching Fa

PY - 2014/2/21

Y1 - 2014/2/21

N2 - An efficient FeCl3 catalyzed protocol for the synthesis of amino functionalized indolylnitroalkanes from easily available precursor indolylnitroalkenes and substituted amines has been developed. Regioselective C-alkylation in the presence of free amino substituted arenes occurred. The scope of this methodology shows good functional group tolerance, and further, this protocol was used to prepare indolylquinoline derivatives.

AB - An efficient FeCl3 catalyzed protocol for the synthesis of amino functionalized indolylnitroalkanes from easily available precursor indolylnitroalkenes and substituted amines has been developed. Regioselective C-alkylation in the presence of free amino substituted arenes occurred. The scope of this methodology shows good functional group tolerance, and further, this protocol was used to prepare indolylquinoline derivatives.

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UR - http://www.scopus.com/inward/citedby.url?scp=84894523122&partnerID=8YFLogxK

U2 - 10.1021/jo4025368

DO - 10.1021/jo4025368

M3 - Article

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AN - SCOPUS:84894523122

SN - 0022-3263

VL - 79

SP - 1842

EP - 1849

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 4

ER -

FeCl3 catalyzed regioselective C -alkylation of indolylnitroalkenes with amino group substituted arenes

摘要

ASJC Scopus subject areas

存取文件

其它文件與鏈接

指紋

資料集

CCDC 966333: Experimental Crystal Structure Determination

CCDC 966332: Experimental Crystal Structure Determination

引用此

FeCl₃ catalyzed regioselective C -alkylation of indolylnitroalkenes with amino group substituted arenes