摘要
The gold(I)-catalyzed Claisen-type rearrangement of cyclic 8-aryl-2,7-enyn-l-ols proceeds via a cationic allylic vinyl ether gold intermediate to give spirocyclic ketones. The reaction proceeded via attack of the hydroxyl group onto the gold-activated alkynes followed by [3,3]-sigmatropic rearrangement to generate the spirocyclic ketones. This transformation can be applied to the synthesis of aza- and oxaspirocyclic ketones from cyclic 8-aryl-2,7-enyn-l-ols bearing an N-sulfonamide or an oxygen atom linkage in the tether and the gold(I) catalyst.
| 原文 | 英語 |
|---|---|
| 頁（從 - 到） | 160-166 |
| 頁數 | 7 |
| 期刊 | Organometallics |
| 卷 | 29 |
| 發行號 | 1 |
| DOIs | |
| 出版狀態 | 已發佈 - 2010 1月 11 |
ASJC Scopus subject areas
- 物理與理論化學
- 有機化學
- 無機化學
指紋
深入研究「Facile synthesis of spirocyclic ketones via gold(I)-catalyzed claisen-type rearrangement of cyclic 8-aryl-2,7-enyn-l-ols」主題。共同形成了獨特的指紋。資料集
-
CCDC 830497: Experimental Crystal Structure Determination
Yeh, M. P. (Creator), Pai, H. (Creator), Hsiow, C. (Creator) & Wang, Y. (Creator), Unknown Publisher, 2011
DOI: 10.5517/ccww675, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccww675&sid=DataCite
資料集: Dataset
-
CCDC 830496: Experimental Crystal Structure Determination
Yeh, M. P. (Creator), Pai, H. (Creator), Hsiow, C. (Creator) & Wang, Y. (Creator), Unknown Publisher, 2011
DOI: 10.5517/ccww664, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccww664&sid=DataCite
資料集: Dataset
-
CCDC 830495: Experimental Crystal Structure Determination
Yeh, M. P. (Creator), Pai, H. (Creator), Hsiow, C. (Creator) & Wang, Y. (Creator), Unknown Publisher, 2011
DOI: 10.5517/ccww653, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccww653&sid=DataCite
資料集: Dataset