Enhancing the tumor discrimination using antibody-activated magnetic nanoparticles in ultra-low magnetic fields

Hong-Chang Yang*, K. W. Huang, S. H. Liao, Herng-Er Horng, J. J. Chieh, H. H. Chen, M. J. Chen, K. L. Chen, L. M. Wang

*此作品的通信作者

研究成果: 雜誌貢獻期刊論文同行評審

9 引文 斯高帕斯(Scopus)

摘要

In this paper, we report an enhanced liver tumor discrimination for rats using antibody-activated magnetic nanoparticles (MNs) and ultra-low-field magnetic resonance imaging ex vivo. It was found that the intensity ratio between the magnetic resonance image of tumor and normal liver tissues is 2-3 absence of antibody-activated MNs in rats. The intensity ratio rises to ∼100 when antibody-activated MNs are expressed in liver tumors through vein injection. Enhancing tumor discrimination using antibody-activated MNs is demonstrated using T1-weighted contrast imaging in ultra-low magnetic fields.

原文英語
文章編號013119
期刊Applied Physics Letters
102
發行號1
DOIs
出版狀態已發佈 - 2013 1月 7

ASJC Scopus subject areas

  • 物理與天文學(雜項)

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