Effectiveness of health checkup with depression screening on depression treatment and outcomes in middle-aged and older adults: a target trial emulation study

Yu Ling Chen, Ming Shiang Wu, Shih Heng Wang, Yin Ju Lien, Shih Cheng Liao, Chia Ming Chang, Wei Lieh Huang, Chi Shin Wu*, Chih Cheng Hsu

*此作品的通信作者

研究成果: 雜誌貢獻期刊論文同行評審

2 引文 斯高帕斯(Scopus)

摘要

Background: Adult preventive health checkups with depression screening were launched in August 2011 in Taiwan; however, its impact has not yet been evaluated. This study aimed to use real-world data to assess the effectiveness of depression screening among middle-aged and older adults. Methods: A total of 4,972,228 adults aged 40 years and above who participated in a health checkup with depression screening between 2013 and 2019 and the same number of unscreened counterparts were included. The target trial emulation study was conducted to estimate the hazard ratios (HRs) for newly treated depression, psychiatric hospitalisation, and suicide. The changes in HRs during the study period were assessed using interval Cox models. Findings: The screening group had a higher rate of newly treated depression (HR 1.63 [95% CI 1.62, 1.64]) and a lower risk of psychiatric hospitalisation (HR 0.93 [95% CI 0.91, 0.95]). There was a null association between depression screening and suicide; however, a higher suicide risk was found in screened older adults aged 65 years and above. Only 10.8% received depression treatment during the study period among the screen-positive individuals. Interpretation: Health checkups with depression screening could potentially promote depression treatment and reduce the risk of psychiatric hospitalisation; however, there was no effect on suicide. The treatment rate for depression remained low after screening for depression. Further attention to enhance referral and treatment is required. Funding: The study was funded by the National Health Research Institutes, Taiwan.

原文英語
文章編號100978
期刊The Lancet Regional Health - Western Pacific
43
DOIs
出版狀態已發佈 - 2024 2月

ASJC Scopus subject areas

  • 內科學
  • 兒科、圍產兒和兒童健康
  • 健康政策
  • 婦產科
  • 公共衛生、環境和職業健康
  • 老年病學和老年學
  • 精神病學和心理健康
  • 傳染性疾病

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