TY - JOUR
T1 - Driven translocation dynamics of polynucleotides through a nanopore
T2 - Off-lattice Monte-Carlo simulations
AU - Chen, C. M.
N1 - Funding Information:
The author acknowledges the support from NSC of Taiwan under Grant No. 92-2112-M-003-005 and from National Taiwan Normal University under Grant No. ORD92-3.
PY - 2005/5/1
Y1 - 2005/5/1
N2 - The driven translocation dynamics of a polynucleotide chain through a nanopore is studied using off-lattice Monte-Carlo simulations, which plays an important role in the nanopore sequencing of polynucleotides. We report a detailed study on the dependence of translocation dynamics on the chain length and the local geometry near the nanopore. In particular, we find that the length dependence of the infection time of the chain could exhibit very different behaviors for different geometries.
AB - The driven translocation dynamics of a polynucleotide chain through a nanopore is studied using off-lattice Monte-Carlo simulations, which plays an important role in the nanopore sequencing of polynucleotides. We report a detailed study on the dependence of translocation dynamics on the chain length and the local geometry near the nanopore. In particular, we find that the length dependence of the infection time of the chain could exhibit very different behaviors for different geometries.
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U2 - 10.1016/j.physa.2004.11.026
DO - 10.1016/j.physa.2004.11.026
M3 - Article
AN - SCOPUS:14644431851
SN - 0378-4371
VL - 350
SP - 95
EP - 107
JO - Physica A: Statistical Mechanics and its Applications
JF - Physica A: Statistical Mechanics and its Applications
IS - 1
ER -