Diversity-Oriented Synthesis of Spirocyclohexene Indane-1,3-diones and Coumarin-Fused Cyclopentanes via an Organobase-Controlled Cascade Reaction

Min Wang, Ping Yao Tseng, Woei Jye Chi, Sundaram Suresh, Athukuri Edukondalu, Yi Ru Chen, Wenwei Lin*

*此作品的通信作者

    研究成果: 雜誌貢獻期刊論文同行評審

    摘要

    An organobase-controlled, divergent cascade reaction to construct spirocyclohexene indane-1,3-diones and coumarin-fused cyclopentanes is reported. The cascade reaction is triggered by the 1,6-addition of 3-homoacylcoumarins to the indanedione-derived acceptors and further regio/chemoselective reaction that preferentially resulted in spiro systems and fused cyclopentanes in a diversity-oriented manner. The 1,6-addition/aldol and 1,6-addition/vinylogous Michael addition cascade processes were controlled by different base/solvent systems to the predominant formation of one of the two carbocyclic compounds. (Figure presented.).

    原文英語
    頁(從 - 到)3407-3415
    頁數9
    期刊Advanced Synthesis and Catalysis
    362
    發行號16
    DOIs
    出版狀態接受/付印 - 2020

    ASJC Scopus subject areas

    • 催化
    • 有機化學

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