Diversity-Oriented Synthesis of Furo[3,2-c]coumarins and Benzofuranyl Chromenones through Chemoselective Acylation/Wittig Reaction

Shu Mei Yang, Chein Yi Wang, Chun Kai Lin, Praneeth Karanam, Ganapuram Madhusudhan Reddy, Yi Ling Tsai, Wenwei Lin

研究成果: 雜誌貢獻文章

16 引文 斯高帕斯(Scopus)

摘要

A highly efficient and chemoselective one-pot protocol for the diversity-oriented synthesis of two types of coumarin-based formal cross-coupling adducts, furo[3,2-c]coumarins and 3-benzofuranyl chromenones, is described. Key attributes of the methodology are an initial chemoselective acylation of functionalized phosphorus zwitterions and a subsequent chemoselective intramolecular Wittig reaction that preferentially resulted in one of the two coumarin derivatives in high yield, depending on relative reactivities and the addition sequence of the acylating agents.

原文英語
頁(從 - 到)1668-1672
頁數5
期刊Angewandte Chemie - International Edition
57
發行號6
DOIs
出版狀態已發佈 - 2018 二月 5

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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