Detection of severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein using AlGaN/GaN high electron mobility transistors

You Ren Hsu, Geng Yen Lee, Jen Inn Chyi, Chung Ke Chang, Chih Cheng Huang, Chen Pin Hsu, Tai Huang Huang, Fan Ren, Yu Lin Wang

研究成果: 書貢獻/報告類型會議貢獻

摘要

AlGaN/GaN high electron mobility transistors (HEMTs) were used to detect the SARS coronavirus (SARS-CoV) nucleocapsid protein interaction without fluorescent labeling. The detection limit in our system was approximately 0.003 nM of protein sample. Our result showed that this technique was more competitive than isotopelabeling EMSA. We demonstrated AlGaN/GaN was highly potential in constructing a semiconductor-based-sensor binding assay to extract the dissociation constants of nucleic acid-protein interaction.

原文英語
主出版物標題Low-Dimensional Nanoscale Electronic and Low-Dimensional Nanoscale Electronic and on Compound Semiconductors 54, SOTAPOCS 2012
頁面239-243
頁數5
版本6
DOIs
出版狀態已發佈 - 2012 十二月 1
事件Symposia on Low-Dimensional Nanoscale Electronic and Photonic Devices 5 and State-of-the-Art Program on Compound Semiconductors 2012, SOTAPOCS 54 - 222nd ECS Meeting/PRiME 2012 - Honolulu, HI, 美国
持續時間: 2012 十月 72012 十月 12

出版系列

名字ECS Transactions
號碼6
50
ISSN(列印)1938-5862
ISSN(電子)1938-6737

其他

其他Symposia on Low-Dimensional Nanoscale Electronic and Photonic Devices 5 and State-of-the-Art Program on Compound Semiconductors 2012, SOTAPOCS 54 - 222nd ECS Meeting/PRiME 2012
國家美国
城市Honolulu, HI
期間12/10/712/10/12

    指紋

ASJC Scopus subject areas

  • Engineering(all)

引用此

Hsu, Y. R., Lee, G. Y., Chyi, J. I., Chang, C. K., Huang, C. C., Hsu, C. P., Huang, T. H., Ren, F., & Wang, Y. L. (2012). Detection of severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein using AlGaN/GaN high electron mobility transistors. 於 Low-Dimensional Nanoscale Electronic and Low-Dimensional Nanoscale Electronic and on Compound Semiconductors 54, SOTAPOCS 2012 (6 編輯, 頁 239-243). (ECS Transactions; 卷 50, 編號 6). https://doi.org/10.1149/05006.0239ecst