摘要
A novel, organobase-catalyzed and highly chemoselective Michael-Michael-acetalization cascade is presented for the efficient synthesis of spiro-indandione skeletons. Following this very simple protocol, a broad range of products was obtained in good yields with excellent diastereocontrol. The role of steric factors in the acetalization step was evaluated.
| 原文 | 英語 |
|---|---|
| 頁（從 - 到） | 9182-9190 |
| 頁數 | 9 |
| 期刊 | Journal of Organic Chemistry |
| 卷 | 82 |
| 發行號 | 17 |
| DOIs | |
| 出版狀態 | 已發佈 - 2017 9月 1 |
ASJC Scopus subject areas
- 有機化學
指紋
深入研究「Chemo- and Diastereoselective Michael-Michael-Acetalization Cascade for the Synthesis of 1,3-Indandione-Fused Spiro[4.5]decan Scaffolds」主題。共同形成了獨特的指紋。資料集
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CCDC 1472949: Experimental Crystal Structure Determination
Yang, S. (Creator), Tsai, Y. (Creator), Reddy, G. M. (Creator), Möhlmann, L. (Creator) & Lin, W. (Creator), Unknown Publisher, 2017
DOI: 10.5517/ccdc.csd.cc1lfqh7, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1lfqh7&sid=DataCite
資料集: Dataset
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CCDC 1472948: Experimental Crystal Structure Determination
Yang, S. (Creator), Tsai, Y. (Creator), Reddy, G. M. (Creator), Möhlmann, L. (Creator) & Lin, W. (Creator), Unknown Publisher, 2017
DOI: 10.5517/ccdc.csd.cc1lfqg6, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1lfqg6&sid=DataCite
資料集: Dataset
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CCDC 1400556: Experimental Crystal Structure Determination
Yang, S. (Creator), Tsai, Y. (Creator), Reddy, G. M. (Creator), Möhlmann, L. (Creator) & Lin, W. (Creator), Unknown Publisher, 2017
DOI: 10.5517/ccdc.csd.cc1j0d75, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1j0d75&sid=DataCite
資料集: Dataset