Chemo- and Diastereoselective Michael-Michael-Acetalization Cascade for the Synthesis of 1,3-Indandione-Fused Spiro[4.5]decan Scaffolds

Shu Mei Yang, Yi Ling Tsai, Ganapuram Madhusudhan Reddy, Lennart Möhlmann, Wenwei Lin*

*此作品的通信作者

研究成果: 雜誌貢獻期刊論文同行評審

10 引文 斯高帕斯(Scopus)

摘要

A novel, organobase-catalyzed and highly chemoselective Michael-Michael-acetalization cascade is presented for the efficient synthesis of spiro-indandione skeletons. Following this very simple protocol, a broad range of products was obtained in good yields with excellent diastereocontrol. The role of steric factors in the acetalization step was evaluated.

原文英語
頁(從 - 到)9182-9190
頁數9
期刊Journal of Organic Chemistry
82
發行號17
DOIs
出版狀態已發佈 - 2017 九月 1

ASJC Scopus subject areas

  • 有機化學

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