Characterizing longitudinal and transverse relaxation rates of ferrofluids in microtesla magnetic fields

Ming Jye Chen, Shu Hsien Liao, Hong Chang Yang*, Hsin Yi Lee, Yi Jia Liu, Hsin Hsien Chen, Herng Er Horng, Shieh Yueh Yang

*此作品的通信作者

研究成果: 雜誌貢獻期刊論文同行評審

8 引文 斯高帕斯(Scopus)

摘要

Shortening spin-lattice relaxation rates (1/T 1) or spin-spin relaxation rates (1/T 2) is the purpose of magnetic resonance imaging contrast agents. In this work, an ultralow field nuclear magnetic resonance spectrometer and imager are set up to characterize the spin relaxation rates of Fe 3O 4 superparamagnetic iron oxide (SPIO) for image contrast. It was found that both 1/T 1 and 1/T 2 increase linearly when the magnetic susceptibility of SPIO increases by increasing the concentration of SPIO dispersed in water. In an applied field, magnetic moments of SPIO generate microscopic field gradients that weaken the field homogeneity, in turn de-phasing the proton's nuclear spin and enhancing the relaxation rates. A T 1-contrast image is demonstrated, using SPIO as the contrast agent and high-T c superconducting quantum interference devices as the detector. T 1-contrast imaging in microtesla fields might provide a potential modality for discriminating cancer.

原文英語
文章編號123911
期刊Journal of Applied Physics
110
發行號12
DOIs
出版狀態已發佈 - 2011 十二月 15

ASJC Scopus subject areas

  • 物理與天文學 (全部)

指紋

深入研究「Characterizing longitudinal and transverse relaxation rates of ferrofluids in microtesla magnetic fields」主題。共同形成了獨特的指紋。

引用此