Asymmetric addition of dimethylzinc to α-ketoesters catalyzed by (-)-MITH

Hsyueh Liang Wu; Ping Yu Wu; Ying Ying Shen; Biing Jiun Uang

doi:10.1021/jo801034q

Asymmetric addition of dimethylzinc to α-ketoesters catalyzed by (-)-MITH

Hsyueh Liang Wu
, Ping Yu Wu
, Ying Ying Shen
, Biing Jiun Uang^*

^*此作品的通信作者

研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

36 引文斯高帕斯（Scopus）

摘要

(Chemical Equation Presented) This investigation describes the catalytic asymmetric addition of dimethylzinc to α-ketoesters in the presence of (-)-MITH (5) and triethyl borate as an additive to give the corresponding chiral α-hydroxy esters with good yields and high enantioselectivities.

原文	英語
頁（從 - 到）	6445-6447
頁數	3
期刊	Journal of Organic Chemistry
卷	73
發行號	16
DOIs	https://doi.org/10.1021/jo801034q
出版狀態	已發佈 - 2008 8月 15
對外發佈	是

ASJC Scopus subject areas

有機化學

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10.1021/jo801034q

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title = "Asymmetric addition of dimethylzinc to α-ketoesters catalyzed by (-)-MITH",

abstract = "(Chemical Equation Presented) This investigation describes the catalytic asymmetric addition of dimethylzinc to α-ketoesters in the presence of (-)-MITH (5) and triethyl borate as an additive to give the corresponding chiral α-hydroxy esters with good yields and high enantioselectivities.",

author = "Wu, \{Hsyueh Liang\} and Wu, \{Ping Yu\} and Shen, \{Ying Ying\} and Uang, \{Biing Jiun\}",

year = "2008",

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doi = "10.1021/jo801034q",

language = "English",

volume = "73",

pages = "6445--6447",

journal = "Journal of Organic Chemistry",

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T1 - Asymmetric addition of dimethylzinc to α-ketoesters catalyzed by (-)-MITH

AU - Wu, Hsyueh Liang

AU - Wu, Ping Yu

AU - Shen, Ying Ying

AU - Uang, Biing Jiun

PY - 2008/8/15

Y1 - 2008/8/15

N2 - (Chemical Equation Presented) This investigation describes the catalytic asymmetric addition of dimethylzinc to α-ketoesters in the presence of (-)-MITH (5) and triethyl borate as an additive to give the corresponding chiral α-hydroxy esters with good yields and high enantioselectivities.

AB - (Chemical Equation Presented) This investigation describes the catalytic asymmetric addition of dimethylzinc to α-ketoesters in the presence of (-)-MITH (5) and triethyl borate as an additive to give the corresponding chiral α-hydroxy esters with good yields and high enantioselectivities.

UR - https://www.scopus.com/pages/publications/50149110222

UR - https://www.scopus.com/pages/publications/50149110222#tab=citedBy

U2 - 10.1021/jo801034q

DO - 10.1021/jo801034q

M3 - Article

C2 - 18646857

AN - SCOPUS:50149110222

SN - 0022-3263

VL - 73

SP - 6445

EP - 6447

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 16

ER -

Asymmetric addition of dimethylzinc to α-ketoesters catalyzed by (-)-MITH

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