Asymmetric addition of diethylzinc to aldehydes catalyzed by a camphor-derived β-amino alcohol

Zhi Long Wu; Hsyueh Liang Wu; Ping Yu Wu; Biing Jiun Uang

doi:10.1016/j.tetasy.2009.06.009

Asymmetric addition of diethylzinc to aldehydes catalyzed by a camphor-derived β-amino alcohol

Zhi Long Wu, Hsyueh Liang Wu, Ping Yu Wu, Biing Jiun Uang^*

^*此作品的通信作者

研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

39 引文斯高帕斯（Scopus）

摘要

The asymmetric addition of diethylzinc to aromatic and aliphatic aldehydes, including linear aliphatic ones, catalyzed by 2 mol % of β-amino alcohol (1S, 2R)-7,7-dimethyl-1-morpholin-4-yl-bicyclo[2.2.1]heptan-2-ol 10 gave the corresponding secondary alcohols in high yields and with up to 94% ee at ambient temperature after 15 min.

原文	英語
頁（從 - 到）	1556-1560
頁數	5
期刊	Tetrahedron Asymmetry
卷	20
發行號	13
DOIs	https://doi.org/10.1016/j.tetasy.2009.06.009
出版狀態	已發佈 - 2009 7月 16
對外發佈	是

ASJC Scopus subject areas

催化
物理與理論化學
有機化學
無機化學

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10.1016/j.tetasy.2009.06.009

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title = "Asymmetric addition of diethylzinc to aldehydes catalyzed by a camphor-derived β-amino alcohol",

abstract = "The asymmetric addition of diethylzinc to aromatic and aliphatic aldehydes, including linear aliphatic ones, catalyzed by 2 mol % of β-amino alcohol (1S, 2R)-7,7-dimethyl-1-morpholin-4-yl-bicyclo[2.2.1]heptan-2-ol 10 gave the corresponding secondary alcohols in high yields and with up to 94% ee at ambient temperature after 15 min.",

author = "Wu, {Zhi Long} and Wu, {Hsyueh Liang} and Wu, {Ping Yu} and Uang, {Biing Jiun}",

note = "Funding Information: We thank the National Science Council, Republic of China, for the financial support.",

year = "2009",

month = jul,

day = "16",

doi = "10.1016/j.tetasy.2009.06.009",

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T1 - Asymmetric addition of diethylzinc to aldehydes catalyzed by a camphor-derived β-amino alcohol

AU - Wu, Zhi Long

AU - Wu, Hsyueh Liang

AU - Wu, Ping Yu

AU - Uang, Biing Jiun

N1 - Funding Information: We thank the National Science Council, Republic of China, for the financial support.

PY - 2009/7/16

Y1 - 2009/7/16

N2 - The asymmetric addition of diethylzinc to aromatic and aliphatic aldehydes, including linear aliphatic ones, catalyzed by 2 mol % of β-amino alcohol (1S, 2R)-7,7-dimethyl-1-morpholin-4-yl-bicyclo[2.2.1]heptan-2-ol 10 gave the corresponding secondary alcohols in high yields and with up to 94% ee at ambient temperature after 15 min.

AB - The asymmetric addition of diethylzinc to aromatic and aliphatic aldehydes, including linear aliphatic ones, catalyzed by 2 mol % of β-amino alcohol (1S, 2R)-7,7-dimethyl-1-morpholin-4-yl-bicyclo[2.2.1]heptan-2-ol 10 gave the corresponding secondary alcohols in high yields and with up to 94% ee at ambient temperature after 15 min.

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U2 - 10.1016/j.tetasy.2009.06.009

DO - 10.1016/j.tetasy.2009.06.009

M3 - Article

AN - SCOPUS:67651102839

SN - 0957-4166

VL - 20

SP - 1556

EP - 1560

JO - Tetrahedron Asymmetry

JF - Tetrahedron Asymmetry

IS - 13

ER -

Asymmetric addition of diethylzinc to aldehydes catalyzed by a camphor-derived β-amino alcohol

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