Anti-peroxidation effect of guava (Psidium guajava Linn.) leaf soluble solids in vitro and in streptozotocin/ nicotinamide-induced diabetic rats

Pei Ting Chuang, Szu Chuan Shen, Ning Jung Wu, James Swi Bea Wu

研究成果: 雜誌貢獻文章同行評審

1 引文 斯高帕斯(Scopus)

摘要

BACKGROUND: Many people in oriental countries, including Japan and Taiwan, believe that guava (Psidium guajava Linn.) leaves are helpful in retarding the progress of type 2 diabetes. This study was conducted to investigate the effect of water-soluble solids (WSS) and ethanol-soluble solids (ESS) of guava leaves on lipid peroxidation in vitro and in type 2 diabetic rats in order to obtain a better understanding of the mechanism of retardation of diabetes. RESULTS: It was found that ESS contained significantly higher total phenolic and flavonoid levels than WSS (P < 0.05). Nevertheless, WSS showed higher superoxide dismutase-like activity and lipid peroxidation inhibition ability than ESS in vitro (P < 0.05). Also, reduced levels of serum triglyceride, low-density lipoprotein and liver thiobarbituric acid-reactive substances were found in type 2 diabetic rats fed with either WSS or ESS as compared with control animals (P < 0.05). CONCLUSION: Anti-peroxidation of lipids is a possible mechanism for guava leaves to retard the progress of diabetes.

原文英語
頁(從 - 到)2173-2179
頁數7
期刊Journal of the Science of Food and Agriculture
88
發行號12
DOIs
出版狀態已發佈 - 2008 九月
對外發佈Yes

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Food Science
  • Chemistry (miscellaneous)

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