Analyze fluorescent characteristic of cancer cell using hyperspectroscopic imaging system (HIS)

Yao Fang Hsieh; Chih Hsien Chen; Ou Yang Mang; Jeng Ren Duann; Jin Chern Chiou; Shun De Wu; Yong Jiun Lin; Ming Hsui Tsai; Nai Wen Chang

doi:10.1117/12.907930

Analyze fluorescent characteristic of cancer cell using hyperspectroscopic imaging system (HIS)

Yao Fang Hsieh^*
, Chih Hsien Chen
, Ou Yang Mang
, Jeng Ren Duann
, Jin Chern Chiou
, Shun De Wu
, Yong Jiun Lin
, Ming Hsui Tsai
, Nai Wen Chang

^*此作品的通信作者

機電工程學系

研究成果: 書貢獻/報告類型 › 會議論文篇章

摘要

Currently, the cancer was examined by diagnosing the pathological changes of tumor. If the examination of cancer can diagnose the tumor before the cell occur the pathological changes, the cure rate of cancer will increase. This research develops a human-machine interface for hyper-spectral microscope. The hyper-spectral microscope can scan the specific area of cell and records the data of spectrum and intensity. These data is helpful to diagnose tumor. This study finds the hyper-spectral imaging have two higher intensity points at 550nm and 700nm, and one lower point at 640nm between the two higher points. For analyzing the hyper-spectral imaging, the intensity at the 550nm peak divided by the intensity at 700nm peak. Finally, we determine the accuracy of detection by Gaussian distribution. The accuracy of detecting normal cells achieves 89%, and the accuracy of cancer cells achieves 81%.

原文	英語
主出版物標題	Three-Dimensional and Multidimensional Microscopy
主出版物子標題	Image Acquisition and Processing XIX
DOIs	https://doi.org/10.1117/12.907930
出版狀態	已發佈 - 2012
事件	Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XIX - San Francisco, CA, 美国持續時間: 2012 1月 24 → 2012 1月 26

出版系列

名字	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
卷	8227
ISSN（列印）	1605-7422

會議

會議	Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XIX
國家/地區	美国
城市	San Francisco, CA
期間	2012/01/24 → 2012/01/26

UN SDG

此研究成果有助於以下永續發展目標

SDG 3 健康與福祉

ASJC Scopus subject areas

電子、光磁材料
生物材料
原子與分子物理與光學
放射學、核子醫學和影像學

存取文件

10.1117/12.907930

其它文件與鏈接

引用此

Hsieh, Y. F., Chen, C. H., Mang, O. Y., Duann, J. R., Chiou, J. C., Wu, S. D., Lin, Y. J., Tsai, M. H., & Chang, N. W. (2012). Analyze fluorescent characteristic of cancer cell using hyperspectroscopic imaging system (HIS). 於 Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XIX 文章 822712 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; 卷 8227). https://doi.org/10.1117/12.907930

Analyze fluorescent characteristic of cancer cell using hyperspectroscopic imaging system (HIS). / Hsieh, Yao Fang; Chen, Chih Hsien; Mang, Ou Yang 等.
Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XIX. 2012. 822712 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; 卷 8227).

研究成果: 書貢獻/報告類型 › 會議論文篇章

Hsieh, YF, Chen, CH, Mang, OY, Duann, JR, Chiou, JC, Wu, SD, Lin, YJ, Tsai, MH & Chang, NW 2012, Analyze fluorescent characteristic of cancer cell using hyperspectroscopic imaging system (HIS). 於 Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XIX., 822712, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 卷 8227, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XIX, San Francisco, CA, 美国, 2012/01/24. https://doi.org/10.1117/12.907930

@inproceedings{33bf291d51954a85a1f6283dba607a9b,

title = "Analyze fluorescent characteristic of cancer cell using hyperspectroscopic imaging system (HIS)",

abstract = "Currently, the cancer was examined by diagnosing the pathological changes of tumor. If the examination of cancer can diagnose the tumor before the cell occur the pathological changes, the cure rate of cancer will increase. This research develops a human-machine interface for hyper-spectral microscope. The hyper-spectral microscope can scan the specific area of cell and records the data of spectrum and intensity. These data is helpful to diagnose tumor. This study finds the hyper-spectral imaging have two higher intensity points at 550nm and 700nm, and one lower point at 640nm between the two higher points. For analyzing the hyper-spectral imaging, the intensity at the 550nm peak divided by the intensity at 700nm peak. Finally, we determine the accuracy of detection by Gaussian distribution. The accuracy of detecting normal cells achieves 89\%, and the accuracy of cancer cells achieves 81\%.",

keywords = "cancer, chacteristic, diagnosis, fluorescence, hyperspectral, microscope",

author = "Hsieh, \{Yao Fang\} and Chen, \{Chih Hsien\} and Mang, \{Ou Yang\} and Duann, \{Jeng Ren\} and Chiou, \{Jin Chern\} and Wu, \{Shun De\} and Lin, \{Yong Jiun\} and Tsai, \{Ming Hsui\} and Chang, \{Nai Wen\}",

year = "2012",

doi = "10.1117/12.907930",

language = "English",

isbn = "9780819488701",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

booktitle = "Three-Dimensional and Multidimensional Microscopy",

note = "Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XIX ; Conference date: 24-01-2012 Through 26-01-2012",

}

TY - GEN

T1 - Analyze fluorescent characteristic of cancer cell using hyperspectroscopic imaging system (HIS)

AU - Hsieh, Yao Fang

AU - Chen, Chih Hsien

AU - Mang, Ou Yang

AU - Duann, Jeng Ren

AU - Chiou, Jin Chern

AU - Wu, Shun De

AU - Lin, Yong Jiun

AU - Tsai, Ming Hsui

AU - Chang, Nai Wen

PY - 2012

Y1 - 2012

N2 - Currently, the cancer was examined by diagnosing the pathological changes of tumor. If the examination of cancer can diagnose the tumor before the cell occur the pathological changes, the cure rate of cancer will increase. This research develops a human-machine interface for hyper-spectral microscope. The hyper-spectral microscope can scan the specific area of cell and records the data of spectrum and intensity. These data is helpful to diagnose tumor. This study finds the hyper-spectral imaging have two higher intensity points at 550nm and 700nm, and one lower point at 640nm between the two higher points. For analyzing the hyper-spectral imaging, the intensity at the 550nm peak divided by the intensity at 700nm peak. Finally, we determine the accuracy of detection by Gaussian distribution. The accuracy of detecting normal cells achieves 89%, and the accuracy of cancer cells achieves 81%.

AB - Currently, the cancer was examined by diagnosing the pathological changes of tumor. If the examination of cancer can diagnose the tumor before the cell occur the pathological changes, the cure rate of cancer will increase. This research develops a human-machine interface for hyper-spectral microscope. The hyper-spectral microscope can scan the specific area of cell and records the data of spectrum and intensity. These data is helpful to diagnose tumor. This study finds the hyper-spectral imaging have two higher intensity points at 550nm and 700nm, and one lower point at 640nm between the two higher points. For analyzing the hyper-spectral imaging, the intensity at the 550nm peak divided by the intensity at 700nm peak. Finally, we determine the accuracy of detection by Gaussian distribution. The accuracy of detecting normal cells achieves 89%, and the accuracy of cancer cells achieves 81%.

KW - cancer

KW - chacteristic

KW - diagnosis

KW - fluorescence

KW - hyperspectral

KW - microscope

UR - https://www.scopus.com/pages/publications/84859613208

UR - https://www.scopus.com/pages/publications/84859613208#tab=citedBy

U2 - 10.1117/12.907930

DO - 10.1117/12.907930

M3 - Conference contribution

AN - SCOPUS:84859613208

SN - 9780819488701

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Three-Dimensional and Multidimensional Microscopy

T2 - Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XIX

Y2 - 24 January 2012 through 26 January 2012

ER -

Analyze fluorescent characteristic of cancer cell using hyperspectroscopic imaging system (HIS)

摘要

出版系列

會議

UN SDG

ASJC Scopus subject areas

存取文件

其它文件與鏈接

指紋

引用此