An expedient stereoselective synthesis of spirocyclopropyl oxindoles from indolin-2-One/N-Protected indolin-2-ones and bromonitroalkenes

Suparna Roy; Kwunmin Chen

doi:10.1002/jccs.201200557

An expedient stereoselective synthesis of spirocyclopropyl oxindoles from indolin-2-One/N-Protected indolin-2-ones and bromonitroalkenes

Suparna Roy, Kwunmin Chen^*

^*此作品的通信作者

化學系

研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

8 引文斯高帕斯（Scopus）

摘要

A direct and much simpler way was developed for the diastereoselective synthesis of spiro cyclopropan- 1,3-oxindoles from indolin-2-one/N-protected indolin-2-ones and bromonitroalkene. The fused restrained cyclopropanes were obtained with high diastereomeric ratios (upto >99:1) and in reasonable to high isolated chemical yields (upto 94%).

原文	英語
頁（從 - 到）	597-604
頁數	8
期刊	Journal of the Chinese Chemical Society
卷	60
發行號	6
DOIs	https://doi.org/10.1002/jccs.201200557
出版狀態	已發佈 - 2013 6月

ASJC Scopus subject areas

一般化學

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10.1002/jccs.201200557

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title = "An expedient stereoselective synthesis of spirocyclopropyl oxindoles from indolin-2-One/N-Protected indolin-2-ones and bromonitroalkenes",

abstract = "A direct and much simpler way was developed for the diastereoselective synthesis of spiro cyclopropan- 1,3-oxindoles from indolin-2-one/N-protected indolin-2-ones and bromonitroalkene. The fused restrained cyclopropanes were obtained with high diastereomeric ratios (upto >99:1) and in reasonable to high isolated chemical yields (upto 94%).",

keywords = "Bromonitroalkene, Cyclopropanation, Diastereoselectivity., Oxindole",

author = "Suparna Roy and Kwunmin Chen",

year = "2013",

month = jun,

doi = "10.1002/jccs.201200557",

language = "English",

volume = "60",

pages = "597--604",

journal = "Journal of the Chinese Chemical Society",

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T1 - An expedient stereoselective synthesis of spirocyclopropyl oxindoles from indolin-2-One/N-Protected indolin-2-ones and bromonitroalkenes

AU - Roy, Suparna

AU - Chen, Kwunmin

PY - 2013/6

Y1 - 2013/6

N2 - A direct and much simpler way was developed for the diastereoselective synthesis of spiro cyclopropan- 1,3-oxindoles from indolin-2-one/N-protected indolin-2-ones and bromonitroalkene. The fused restrained cyclopropanes were obtained with high diastereomeric ratios (upto >99:1) and in reasonable to high isolated chemical yields (upto 94%).

AB - A direct and much simpler way was developed for the diastereoselective synthesis of spiro cyclopropan- 1,3-oxindoles from indolin-2-one/N-protected indolin-2-ones and bromonitroalkene. The fused restrained cyclopropanes were obtained with high diastereomeric ratios (upto >99:1) and in reasonable to high isolated chemical yields (upto 94%).

KW - Bromonitroalkene

KW - Cyclopropanation

KW - Diastereoselectivity.

KW - Oxindole

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DO - 10.1002/jccs.201200557

M3 - Article

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VL - 60

SP - 597

EP - 604

JO - Journal of the Chinese Chemical Society

JF - Journal of the Chinese Chemical Society

IS - 6

ER -

An expedient stereoselective synthesis of spirocyclopropyl oxindoles from indolin-2-One/N-Protected indolin-2-ones and bromonitroalkenes

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