An enantioselective cascade for simultaneous generation of five quaternary stereocenters from fully substituted enones

Shu Mei Yang, Ganapuram Madhusudhan Reddy, Tzu Ping Wang, Yu Sheng Yeh, Min Wang, Wenwei Lin

研究成果: 雜誌貢獻期刊論文同行評審

19 引文 斯高帕斯(Scopus)

摘要

A highly enantioselective cascade reaction for the generation of five quaternary stereocenters in one-pot operation is reported for the first time in the history of organic synthesis. Cinchona-alkaloid derived hydrogen-bonding catalyst furnished structurally complex cascade products from simple substrates in excellent yields and stereoselectivities.

原文英語
頁(從 - 到)7649-7652
頁數4
期刊Chemical Communications
53
發行號54
DOIs
出版狀態已發佈 - 2017

ASJC Scopus subject areas

  • 催化
  • 電子、光磁材料
  • 陶瓷和複合材料
  • 一般化學
  • 表面、塗料和薄膜
  • 金屬和合金
  • 材料化學

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