Advances in biomagnetic research using high- Tc superconducting quantum interference devices

Hong-Chang Yang, Herng-Er Horng, Shieh-Yueh Yang, Shu-Hsien Liao

研究成果: 雜誌貢獻综述文章

12 引文 斯高帕斯(Scopus)

摘要

This review reports the advances of biomagnetic research using high- T c superconducting quantum interference devices (SQUIDs). It especially focuses on SQUID-detected magnetocardiography (MCG), magnetically labeled immunoassays (MLIs) as well as nuclear magnetic resonance and imaging (NMR/MRI). The progress in MCG that scientists have made and the encountered challenges are discussed here. This study includes the early detection of the electromagnetic change in cardiac activity in animal studies of hypercholesterolemic rabbits, which suggests the possibility of early diagnosis of cardiac disease in clinical applications. The progress on MLIs using measurements of remanence, magnetic relaxation and magnetic susceptibility reduction is presented. The wash-free immunomagnetic reduction shows both high sensitivity and high specificity. NMR/MRI of high spectral resolution and of high signal-to-noise ratio are addressed and discussed. The proton-phosphate J-coupling of trimethyl phosphate ((CH3)3PO4) in one shot in microtesla fields is demonstrated. The prospects of biomagnetic applications are addressed.

原文英語
文章編號093001
期刊Superconductor Science and Technology
22
發行號9
DOIs
出版狀態已發佈 - 2009 九月 10

ASJC Scopus subject areas

  • Ceramics and Composites
  • Condensed Matter Physics
  • Metals and Alloys
  • Electrical and Electronic Engineering
  • Materials Chemistry

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