A Water-Soluble Rhenium(I) Catalyst for the Regio- And Stereoselective C(sp2)-H Alkenylation of N-Pyridyl-/ N-Pyrimidylindole and the N-H Alkenylation of N-Pyrimidylaniline Derivatives with Ynamides

Sundaramoorthi Sarathkumar; Veerababurao Kavala; Ching Fa Yao

doi:10.1021/acs.orglett.0c04068

A Water-Soluble Rhenium(I) Catalyst for the Regio- And Stereoselective C(sp²)-H Alkenylation of N-Pyridyl-/ N-Pyrimidylindole and the N-H Alkenylation of N-Pyrimidylaniline Derivatives with Ynamides

Sundaramoorthi Sarathkumar, Veerababurao Kavala, Ching Fa Yao^*

^*此作品的通信作者

化學系

研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

10 引文斯高帕斯（Scopus）

摘要

A water-soluble and low-valent rhenium(I) catalyst for the C2 alkenylation of N-pyridyl/N-pyrimidylindole derivatives with ynamides under mild conditions using water as the solvent has been described. The reaction of N-pyridyl/N-pyrimidyl indole with the ynamide afforded the C2-Z-selective alkenylation derivative as the sole product, and the reactions of N-pyrimidylanilines delivered the corresponding N-alkenylated product rather than the expected C-H alkenylation products in high yields under the same conditions.

原文	英語
頁（從 - 到）	1960-1965
頁數	6
期刊	Organic Letters
卷	23
發行號	6
DOIs	https://doi.org/10.1021/acs.orglett.0c04068
出版狀態	已發佈 - 2021 3月 19

ASJC Scopus subject areas

生物化學
物理與理論化學
有機化學

存取文件

10.1021/acs.orglett.0c04068

其它文件與鏈接

CCDC 2047929: Experimental Crystal Structure Determination
Sarathkumar, S. (Contributor), Kavala, V. (Contributor) & Yao, C. (Contributor), The Cambridge Structural Database, 2021
DOI: 10.5517/ccdc.csd.cc26r178, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc26r178&sid=DataCite
資料集: Dataset
CCDC 2047932: Experimental Crystal Structure Determination
Sarathkumar, S. (Contributor), Kavala, V. (Contributor) & Yao, C. (Contributor), The Cambridge Structural Database, 2021
DOI: 10.5517/ccdc.csd.cc26r1bc, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc26r1bc&sid=DataCite
資料集: Dataset
CCDC 2047931: Experimental Crystal Structure Determination
Sarathkumar, S. (Contributor), Kavala, V. (Contributor) & Yao, C. (Contributor), The Cambridge Structural Database, 2021
DOI: 10.5517/ccdc.csd.cc26r19b, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc26r19b&sid=DataCite
資料集: Dataset

引用此

A Water-Soluble Rhenium(I) Catalyst for the Regio- And Stereoselective C(sp²)-H Alkenylation of N-Pyridyl-/ N-Pyrimidylindole and the N-H Alkenylation of N-Pyrimidylaniline Derivatives with Ynamides. / Sarathkumar, Sundaramoorthi; Kavala, Veerababurao; Yao, Ching Fa.
於: Organic Letters, 卷 23, 編號 6, 19.03.2021, p. 1960-1965.

研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

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A Water-Soluble Rhenium(I) Catalyst for the Regio- And Stereoselective C(sp2)-H Alkenylation of N-Pyridyl-/ N-Pyrimidylindole and the N-H Alkenylation of N-Pyrimidylaniline Derivatives with Ynamides

摘要

ASJC Scopus subject areas

存取文件

其它文件與鏈接

指紋

資料集

CCDC 2047929: Experimental Crystal Structure Determination

CCDC 2047932: Experimental Crystal Structure Determination

CCDC 2047931: Experimental Crystal Structure Determination

引用此

A Water-Soluble Rhenium(I) Catalyst for the Regio- And Stereoselective C(sp²)-H Alkenylation of N-Pyridyl-/ N-Pyrimidylindole and the N-H Alkenylation of N-Pyrimidylaniline Derivatives with Ynamides