A simple and facile route for the synthesis of 2H-1,4-benzoxazin-3-(4H)- ones via reductive cyclization of 2-(2-nitrophenoxy)acetonitrile adducts in the presence of Fe/acetic acid

Chintakunta Ramesh; B. Rama Raju; Veerababurao Kavala; Chun Wei Kuo; Ching Fa Yao

doi:10.1016/j.tet.2010.11.095

A simple and facile route for the synthesis of 2H-1,4-benzoxazin-3-(4H)- ones via reductive cyclization of 2-(2-nitrophenoxy)acetonitrile adducts in the presence of Fe/acetic acid

Chintakunta Ramesh
, B. Rama Raju
, Veerababurao Kavala
, Chun Wei Kuo
, Ching Fa Yao^*

^*此作品的通信作者

化學系

研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

32 引文斯高帕斯（Scopus）

摘要

A simple route for the synthesis of 1,4-benzoxazin-3-(4H)-ones is described herein. This method involves the reductive cyclization of 2-(2-nitrophenoxy) acetonitrile adducts in the presence of Fe/acetic acid in good to excellent yields. This system was compatible with various other functional groups.

原文	英語
頁（從 - 到）	1187-1192
頁數	6
期刊	Tetrahedron
卷	67
發行號	6
DOIs	https://doi.org/10.1016/j.tet.2010.11.095
出版狀態	已發佈 - 2011 2月 11

ASJC Scopus subject areas

生物化學
藥物發現
有機化學

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10.1016/j.tet.2010.11.095

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title = "A simple and facile route for the synthesis of 2H-1,4-benzoxazin-3-(4H)- ones via reductive cyclization of 2-(2-nitrophenoxy)acetonitrile adducts in the presence of Fe/acetic acid",

abstract = "A simple route for the synthesis of 1,4-benzoxazin-3-(4H)-ones is described herein. This method involves the reductive cyclization of 2-(2-nitrophenoxy) acetonitrile adducts in the presence of Fe/acetic acid in good to excellent yields. This system was compatible with various other functional groups.",

author = "Chintakunta Ramesh and Raju, \{B. Rama\} and Veerababurao Kavala and Kuo, \{Chun Wei\} and Yao, \{Ching Fa\}",

note = "Funding Information: Financial support for this work by the National Science Council of the Republic of China and the National Taiwan Normal University ( 99T3030-2 ) is gratefully acknowledged. ",

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AU - Ramesh, Chintakunta

AU - Raju, B. Rama

AU - Kavala, Veerababurao

AU - Kuo, Chun Wei

AU - Yao, Ching Fa

N1 - Funding Information: Financial support for this work by the National Science Council of the Republic of China and the National Taiwan Normal University ( 99T3030-2 ) is gratefully acknowledged.

PY - 2011/2/11

Y1 - 2011/2/11

N2 - A simple route for the synthesis of 1,4-benzoxazin-3-(4H)-ones is described herein. This method involves the reductive cyclization of 2-(2-nitrophenoxy) acetonitrile adducts in the presence of Fe/acetic acid in good to excellent yields. This system was compatible with various other functional groups.

AB - A simple route for the synthesis of 1,4-benzoxazin-3-(4H)-ones is described herein. This method involves the reductive cyclization of 2-(2-nitrophenoxy) acetonitrile adducts in the presence of Fe/acetic acid in good to excellent yields. This system was compatible with various other functional groups.

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DO - 10.1016/j.tet.2010.11.095

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A simple and facile route for the synthesis of 2H-1,4-benzoxazin-3-(4H)- ones via reductive cyclization of 2-(2-nitrophenoxy)acetonitrile adducts in the presence of Fe/acetic acid

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