A simple and facile route for the synthesis of 2H-1,4-benzoxazin-3-(4H)- ones via reductive cyclization of 2-(2-nitrophenoxy)acetonitrile adducts in the presence of Fe/acetic acid

Chintakunta Ramesh, B. Rama Raju, Veerababurao Kavala, Chun Wei Kuo, Ching Fa Yao*

*此作品的通信作者

研究成果: 雜誌貢獻期刊論文同行評審

27 引文 斯高帕斯(Scopus)

摘要

A simple route for the synthesis of 1,4-benzoxazin-3-(4H)-ones is described herein. This method involves the reductive cyclization of 2-(2-nitrophenoxy) acetonitrile adducts in the presence of Fe/acetic acid in good to excellent yields. This system was compatible with various other functional groups.

原文英語
頁(從 - 到)1187-1192
頁數6
期刊Tetrahedron
67
發行號6
DOIs
出版狀態已發佈 - 2011 二月 11

ASJC Scopus subject areas

  • 生物化學
  • 藥物發現
  • 有機化學

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