A selective glucose sensor: The cooperative effect of monoboronic acid-modified poly(amidoamine) dendrimers

Ching Hua Tsai; Yi Hsuan Tang; Hui Ting Chen; Yi Wen Yao; Tun Cheng Chien; Chai Lin Kao

doi:10.1039/c8cc00914g

A selective glucose sensor: The cooperative effect of monoboronic acid-modified poly(amidoamine) dendrimers

Ching Hua Tsai, Yi Hsuan Tang, Hui Ting Chen, Yi Wen Yao, Tun Cheng Chien^*, Chai Lin Kao

^*此作品的通信作者

化學系

研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

12 引文斯高帕斯（Scopus）

摘要

Selective glucose binding was identified through five generations of monoboronic acid-functionalized PAMAM dendrimers. The best selectivity obtained when using G3 dendrimers (1b) generated 71.1, 94.9, and 1309 times stronger binding than when using galactose, fructose, and lactose, respectively. Further experiments using dendrimer analogues and glucose derivatives suggested that two nearby monoboronic acids cooperatively bound one glucose.

原文	英語
頁（從 - 到）	4577-4580
頁數	4
期刊	Chemical Communications
卷	54
發行號	36
DOIs	https://doi.org/10.1039/c8cc00914g
出版狀態	已發佈 - 2018

ASJC Scopus subject areas

催化
電子、光磁材料
陶瓷和複合材料
一般化學
表面、塗料和薄膜
金屬和合金
材料化學

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10.1039/c8cc00914g

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abstract = "Selective glucose binding was identified through five generations of monoboronic acid-functionalized PAMAM dendrimers. The best selectivity obtained when using G3 dendrimers (1b) generated 71.1, 94.9, and 1309 times stronger binding than when using galactose, fructose, and lactose, respectively. Further experiments using dendrimer analogues and glucose derivatives suggested that two nearby monoboronic acids cooperatively bound one glucose.",

author = "Tsai, {Ching Hua} and Tang, {Yi Hsuan} and Chen, {Hui Ting} and Yao, {Yi Wen} and Chien, {Tun Cheng} and Kao, {Chai Lin}",

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doi = "10.1039/c8cc00914g",

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T2 - The cooperative effect of monoboronic acid-modified poly(amidoamine) dendrimers

AU - Tsai, Ching Hua

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AU - Chen, Hui Ting

AU - Yao, Yi Wen

AU - Chien, Tun Cheng

AU - Kao, Chai Lin

PY - 2018

Y1 - 2018

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AB - Selective glucose binding was identified through five generations of monoboronic acid-functionalized PAMAM dendrimers. The best selectivity obtained when using G3 dendrimers (1b) generated 71.1, 94.9, and 1309 times stronger binding than when using galactose, fructose, and lactose, respectively. Further experiments using dendrimer analogues and glucose derivatives suggested that two nearby monoboronic acids cooperatively bound one glucose.

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JO - Chemical Communications

JF - Chemical Communications

IS - 36

ER -

A selective glucose sensor: The cooperative effect of monoboronic acid-modified poly(amidoamine) dendrimers

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