摘要
The 1,1-diorganometallics of magnesium and zinc 1 are converted by the reaction with Me3SnCl to the 1,1-diorganometallics of tin and zinc 2 which are readily oxidized by dry air at -10° to 0°C to afford the corresponding aldehydes and ketones 3 in 57-91% yield. This mild oxidation reaction allows a new stereoselective approach to aldol products. An extension of the reaction to 1,1-diorganometallics of silicon and zinc is described.
原文 | 英語 |
---|---|
頁(從 - 到) | 6697-6700 |
頁數 | 4 |
期刊 | Tetrahedron Letters |
卷 | 29 |
發行號 | 51 |
DOIs | |
出版狀態 | 已發佈 - 1988 |
對外發佈 | 是 |
ASJC Scopus subject areas
- 生物化學
- 藥物發現
- 有機化學