A dual-mode radio frequency DNA sensor

J. H. Chien, C. H. Chang, Y. F. Hsieh, D. S. Lee, L. S. Kuo, C. H. Yang, C. R. Yang, W. P. Chou, P. H. Chen*

*此作品的通信作者

研究成果: 書貢獻/報告類型會議論文篇章

摘要

Different from traditional detection methods which were expensive and time consuming for biochemical analyses, a DNA chip assay by using gold nanoparticles (AuNPs) immunological amplification methods and radio frequency techniques was applied to detect DNA sequences rapidly and conveniently. First the capture DNA (cDNA) was immobilized to the substrate on which the LC shunt located. Then the target DNA (tDNA) and probe DNA (pDNA) with AuNP at the 3' end were added to form AuNP-linking structures. Furthermore, the SU and S21 curves of the biosensors changed due to the AuNP-linking structures between the interdigital and meander waveguides. The changes in S11 and S21 determined whether the tDNA existed. Due to the dual-mode design of the DNA sensors, this platform has a potential for multisample detection. The study provided an alternatively simple, fast and convenient solution for biochemical detection

原文英語
主出版物標題Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007
頁面532-536
頁數5
DOIs
出版狀態已發佈 - 2007
事件2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007 - Bangkok, 泰国
持續時間: 2007 一月 162007 一月 19

出版系列

名字Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007

其他

其他2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007
國家/地區泰国
城市Bangkok
期間2007/01/162007/01/19

ASJC Scopus subject areas

  • 電腦網路與通信
  • 電腦科學應用
  • 電氣與電子工程

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