A convenient preparation of 1,2,3-tri-O-acetyl-β-D-ribofuranose by enzymatic regioselective 5-O-deacetylation of the peracetylated ribofuranose

Tun Cheng Chien; Ji Wang Chern

doi:10.1016/j.carres.2004.01.010

A convenient preparation of 1,2,3-tri-O-acetyl-β-D-ribofuranose by enzymatic regioselective 5-O-deacetylation of the peracetylated ribofuranose

Tun Cheng Chien
, Ji Wang Chern^*

^*此作品的通信作者

研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

18 引文斯高帕斯（Scopus）

摘要

The lipase from Candida rugosa (Sigma) was used to catalyze the regioselective deacetylation at the 5-position of 1,2,3,5-tetra-O-acetyl-β- D-ribofuranose on a preparative scale. Enzymatic deacetylation provides a convenient one-step preparation of 1,2,3-tri-O-acetyl-β-D-ribofuranose.

原文	英語
頁（從 - 到）	1215-1217
頁數	3
期刊	Carbohydrate Research
卷	339
發行號	6
DOIs	https://doi.org/10.1016/j.carres.2004.01.010
出版狀態	已發佈 - 2004 4月 28
對外發佈	是

ASJC Scopus subject areas

分析化學
生物化學
有機化學

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10.1016/j.carres.2004.01.010

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@article{7122478abc5549c98fb3f355b974f538,

title = "A convenient preparation of 1,2,3-tri-O-acetyl-β-D-ribofuranose by enzymatic regioselective 5-O-deacetylation of the peracetylated ribofuranose",

abstract = "The lipase from Candida rugosa (Sigma) was used to catalyze the regioselective deacetylation at the 5-position of 1,2,3,5-tetra-O-acetyl-β- D-ribofuranose on a preparative scale. Enzymatic deacetylation provides a convenient one-step preparation of 1,2,3-tri-O-acetyl-β-D-ribofuranose.",

keywords = "Deacetylation, Deprotection, Lipase, Regioselective, Ribofuranose",

author = "Chien, \{Tun Cheng\} and Chern, \{Ji Wang\}",

note = "Funding Information: This investigation was supported by a research grant (NSC90-2321-B002-002) from the National Science Council of Taiwan.",

year = "2004",

month = apr,

day = "28",

doi = "10.1016/j.carres.2004.01.010",

language = "English",

volume = "339",

pages = "1215--1217",

journal = "Carbohydrate Research",

issn = "0008-6215",

publisher = "Elsevier Limited",

number = "6",

}

TY - JOUR

T1 - A convenient preparation of 1,2,3-tri-O-acetyl-β-D-ribofuranose by enzymatic regioselective 5-O-deacetylation of the peracetylated ribofuranose

AU - Chien, Tun Cheng

AU - Chern, Ji Wang

N1 - Funding Information: This investigation was supported by a research grant (NSC90-2321-B002-002) from the National Science Council of Taiwan.

PY - 2004/4/28

Y1 - 2004/4/28

N2 - The lipase from Candida rugosa (Sigma) was used to catalyze the regioselective deacetylation at the 5-position of 1,2,3,5-tetra-O-acetyl-β- D-ribofuranose on a preparative scale. Enzymatic deacetylation provides a convenient one-step preparation of 1,2,3-tri-O-acetyl-β-D-ribofuranose.

AB - The lipase from Candida rugosa (Sigma) was used to catalyze the regioselective deacetylation at the 5-position of 1,2,3,5-tetra-O-acetyl-β- D-ribofuranose on a preparative scale. Enzymatic deacetylation provides a convenient one-step preparation of 1,2,3-tri-O-acetyl-β-D-ribofuranose.

KW - Deacetylation

KW - Deprotection

KW - Lipase

KW - Regioselective

KW - Ribofuranose

UR - https://www.scopus.com/pages/publications/1942453234

UR - https://www.scopus.com/pages/publications/1942453234#tab=citedBy

U2 - 10.1016/j.carres.2004.01.010

DO - 10.1016/j.carres.2004.01.010

M3 - Article

C2 - 15063214

AN - SCOPUS:1942453234

SN - 0008-6215

VL - 339

SP - 1215

EP - 1217

JO - Carbohydrate Research

JF - Carbohydrate Research

IS - 6

ER -

A convenient preparation of 1,2,3-tri-O-acetyl-β-D-ribofuranose by enzymatic regioselective 5-O-deacetylation of the peracetylated ribofuranose

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