尋找研究成果

搜尋結果

• 2020

  Copper-catalysed synthesis of 3-hydroxyisoindolin-1-ones from benzylcyanide 2-iodobenzamides

  Kavala, V., Wang, C. Y., Wang, C. C., Patil, P. B., Fang, C. C., Kuo, C. W. & Yao, C. F., 2020 一月 1, 於: Organic and Biomolecular Chemistry. 18, 5, p. 988-998 11 p.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • benzyl cyanide
  • cyanides
  • cesium carbonate
  • Copper
  • Derivatives
  1 引文 斯高帕斯（Scopus）

• Pathomechanism characterization and potential therapeutics identification for SCA3 targeting neuroinflammation

  Chiu, Y. J., Lin, S. A., Chen, W. L., Lin, T. H., Lin, C. H., Yao, C. F., Lin, W., Wu, Y. R., Chang, K. H., Lee-Chen, G. J. & Chen, C. M., 2020 十二月, 於: Aging. 12, 23, p. 23619-23646 28 p.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • polyglutamine
  • N-(4-hydroxyphenyl)arachidonylamide
  • Microglia
  • Interleukin-1
  • 4-aminophenol

• Synthesis of Pyrido[2,3-b]indoles via Brønsted-Acid-Promoted Decarboxylative Annulation of 3-Bromopropenals and Ethyl 2-Amino-1H-indole-3-carboxylates

  Yang, T. H., Kavala, V., Kuo, C. W. & Yao, C. F., 2020 七月 1, 於: Asian Journal of Organic Chemistry. 9, 7, p. 1053-1058 6 p.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • Carbolines
  • Indoles
  • indole
  • Derivatives
  • Acids
  1 引文 斯高帕斯（Scopus）
• 2019

  A Synthetic Strategy for the Construction of Functionalized Triphenylene Frameworks via Palladium Catalyzed Intramolecular Annulation/Decyanogenative C-H Bond Alkenylation

  Ichake, S. S., Villuri, B. K., Reddy, S. R., Kavala, V. & Yao, C. F., 2019 一月 1, 於: Organic Letters. 21, 7, p. 2256-2260 5 p.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • Alkenylation
  • triphenylene
  • benzyl cyanide
  • Palladium
  • cyanides
  2 引文 斯高帕斯（Scopus）

• Indole compound NC009-1 augments APOE and TRKA in Alzheimer's disease cell and mouse models for neuroprotection and cognitive improvement

  Chen, Y. C., Chiu, Y. J., Lin, C. H., Hsu, W. C., Wu, J. L., Huang, C. H., Lin, C. W., Yao, C. F., Huang, H. J., Lo, Y. S., Chen, C. M., Wu, Y. R., Chang, K. H., Lee-Chen, G. J. & Hsieh-Li, H. M., 2019 一月 1, 於: Journal of Alzheimer's Disease. 67, 2, p. 737-756 20 p.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • tropomyosin kinase
  • Low Density Lipoprotein Receptor-Related Protein-1
  • indole
  • Neuroprotection
  • Alzheimer Disease
  4 引文 斯高帕斯（Scopus）

• Microwave-Assisted Ruthenium(II)-Catalyzed C−H/N−O Activation of N-Methoxybenzamides with Alkynylsulfane

  Sarathkumar, S., Kavala, V. & Yao, C. F., 2019 十月 1, 於: Asian Journal of Organic Chemistry. 8, 10, p. 1830-1833 4 p.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • Ruthenium
  • Chemical activation
  • Microwaves
  • Derivatives
  3 引文 斯高帕斯（Scopus）

• Neuroprotection of Indole-Derivative Compound NC001-8 by the Regulation of the NRF2 Pathway in Parkinson's Disease Cell Models

  Wei, P. C., Lee-Chen, G. J., Chen, C. M., Wu, Y. R., Chen, Y. J., Lin, J. L., Lo, Y. S., Yao, C. F. & Chang, K. H., 2019, 於: Oxidative medicine and cellular longevity. 2019, 5074367.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  開啟存取

  • indole
  • Neuroprotection
  • Dopaminergic Neurons
  • Parkinson Disease
  • Derivatives
  9 引文 斯高帕斯（Scopus）

• Synthesis of Polysubstituted Cyclopentene and Cyclopenta[ b]carbazole Analogues from Unsymmetrical 4-Arylidene-3,6-diarylhex-2-en-5-ynal and Indole Derivatives via an Iodine Mediated Electrocyclization Reaction

  Bandi, V., Kavala, V., Konala, A., Hsu, C. H., Villuri, B. K., Reddy, S. R., Lin, L., Kuo, C. W. & Yao, C. F., 2019 三月 15, 於: Journal of Organic Chemistry. 84, 6, p. 3036-3044 9 p.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • Cyclopentanes
  • carbazole
  • Indoles
  • indole
  • 7-methylindole
  2 引文 斯高帕斯（Scopus）
• 2018

  A triazole-conjugated benzoxazone induces reactive oxygen species and promotes autophagic apoptosis in human lung cancer cells

  Hsieh, C. H., Wang, J. P., Chiu, C. C., Liu, C. Y., Yao, C. F. & Fang, K., 2018 一月 1, 於: Apoptosis. 23, 1

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • Triazoles
  • Tumors
  • Cells
  • Reactive Oxygen Species
  • Lung Neoplasms
  6 引文 斯高帕斯（Scopus）

• Copper-Catalyzed Cascade Synthesis of 2-Aryl-3-cyanobenzofuran and Dibenzo[ b, f]oxepine-10-carbonitrile Derivatives

  Villuri, B. K., Ichake, S. S., Reddy, S. R., Kavala, V., Bandi, V., Kuo, C. W. & Yao, C. F., 2018 九月 7, 於: Journal of Organic Chemistry. 83, 17, p. 10241-10247 7 p.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • Oxepins
  • Hydroxylation
  • Copper
  • Condensation
  • Benzaldehydes
  8 引文 斯高帕斯（Scopus）

• Synthesis of 1,2,3-Fused Indole Polyheterocycles by Copper-Catalyzed Cascade Reaction

  Kavala, V., Yang, Z., Konala, A., Yang, T. H., Kuo, C. W., Ruan, J. Y. & Yao, C. F., 2018 三月 14, 於: European Journal of Organic Chemistry. 2018, 10, p. 1241-1247 7 p.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • indoles
  • cyanides
  • indole
  • Cyanides
  • reaction time
  8 引文 斯高帕斯（Scopus）

• The indole compound NC009-1 inhibits aggregation and promotes neurite outgrowth through enhancement of HSPB1 in SCA17 cells and ameliorates the behavioral deficits in SCA17 mice

  Chen, C. M., Chen, W. L., Hung, C. T., Lin, T. H., Chao, C. Y., Lin, C. H., Wu, Y. R., Chang, K. H., Yao, C. F., Lee-Chen, G. J., Su, M. T. & Hsieh-Li, H. M., 2018 七月 1, 於: NeuroToxicology. 67, p. 259-269 11 p.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • Spinocerebellar Ataxia 17
  • TATA-Box Binding Protein
  • indole
  • Neuronal Outgrowth
  • Agglomeration
  11 引文 斯高帕斯（Scopus）
• 2017

  A Copper-Catalyzed Cascade Approach for the Synthesis of Dibenzo[b,f]1,8-naphthyridine Derivatives

  Villuri, B. K., Konala, A., Kavala, V., Kotipalli, T., Kuo, C. W. & Yao, C. F., 2017 九月 18, 於: Advanced Synthesis and Catalysis. 359, 18, p. 3142-3153 12 p.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • Naphthyridines
  • Copper
  • Derivatives
  • Alkynes
  • Nitriles
  5 引文 斯高帕斯（Scopus）

• A potent indolylquinoline alleviates growth of human lung cancer cell tumorspheres

  Ni, Y. L., Hsieh, C. H., Kim, S. H., Wang, J. P., Su, C. L., Yao, C. F. & Fang, K., 2017 十月 1, 於: Apoptosis. 22, 10, p. 1235-1245 11 p.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • Cells
  • 3-((7-ethyl-1H-indol-3-yl)-methyl)-2-methylquinoline
  • Lung Neoplasms
  • Tumors
  • Mitochondria
  1 引文 斯高帕斯（Scopus）

• Palladium-catalyzed tandem C-H functionalization/cyclization strategy for the synthesis of 5-hydroxybenzofuran derivatives

  Ichake, S. S., Konala, A., Kavala, V., Kuo, C. W. & Yao, C. F., 2017 一月 6, 於: Organic Letters. 19, 1, p. 54-57 4 p.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • Cyclization
  • alkynes
  • Alkynes
  • Palladium
  • quinones
  19 引文 斯高帕斯（Scopus）

• Regioselective switching approach for the synthesis of α and δ carboline derivatives

  Yang, T. H., Kuo, C. W., Kavala, V., Konala, A., Huang, C. Y. & Yao, C. F., 2017, 於: Chemical Communications. 53, 10, p. 1676-1679 4 p.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • Carbolines
  • Oximes
  • Derivatives
  • Esters
  • Metals
  14 引文 斯高帕斯（Scopus）

• Synthesis of Benzopyridoindolone Derivatives via a One-Pot Copper Catalyzed Tandem Reaction of 2-Iodobenzamide Derivatives and 2-Iodobenzylcyanides

  Kavala, V., Yang, Z., Konala, A., Huang, C. Y., Kuo, C. W. & Yao, C. F., 2017 七月 21, 於: Journal of Organic Chemistry. 82, 14, p. 7280-7286 7 p.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • indole
  • Copper
  • Pyridones
  • Derivatives
  • Thiophenes
  12 引文 斯高帕斯（Scopus）

• Synthesis of Biologically Active Indenoisoquinoline Derivatives via a One-Pot Copper(II)-Catalyzed Tandem Reaction

  Huang, C. Y., Kavala, V., Kuo, C. W., Konala, A., Yang, T. H. & Yao, C. F., 2017 二月 17, 於: Journal of Organic Chemistry. 82, 4, p. 1961-1968 8 p.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • NSC 314622
  • cesium carbonate
  • NSC 724998
  • 1,2-indanedione
  • cupric chloride
  22 引文 斯高帕斯（Scopus）

• Synthesis of functionalized unsymmetrical 1,3-butadiene-3-yne derivatives from β-halo styrene derivatives and their application in the synthesis of trisubstituted pyridines

  Bandi, V., Kavala, V., Hsu, C. H., Konala, A., Villuri, B. K., Kotipalli, T., Kuo, C. W. & Yao, C. F., 2017, 於: RSC Advances. 7, 74, p. 46704-46712 9 p.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • Pyridines
  • Pyridine
  • 1,3-butadiene
  • Styrene
  • Butadiene
  2 引文 斯高帕斯（Scopus）

• The Potential of Indole/Indolylquinoline Compounds in Tau Misfolding Reduction by Enhancement of HSPB1

  Chang, K. H., Lin, C. H., Chen, H. C., Huang, H. Y., Chen, S. L., Lin, T. H., Ramesh, C., Huang, C. C., Fung, H. C., Wu, Y. R., Huang, H. J., Lee-Chen, G. J., Hsieh-Li, H. M. & Yao, C. F., 2017 一月 1, 於: CNS Neuroscience and Therapeutics. 23, 1, p. 45-56 12 p.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • indole
  • fluorescent protein 583
  • Neuronal Outgrowth
  • Alzheimer Disease
  • Solubility
  10 引文 斯高帕斯（Scopus）

• Using gene expression database to uncover biology functions of 1,4-disubstituted 1,2,3-triazole analogues synthesized via a copper (I)-catalyzed reaction

  Su, C. L., Tseng, C. L., Ramesh, C., Liu, H. S., Huang, C. Y. F. & Yao, C. F., 2017, 於: European Journal of Medicinal Chemistry. 132, p. 90-107 18 p.

  研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

  • N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea
  • Cytotoxicity
  • Triazoles
  • Gene expression
  • Cycloaddition
  16 引文 斯高帕斯（Scopus）