Trade-offs between elimination and detoxification in rainbow trout and common bivalve molluscs exposed to metal stressors

Yun Ru Ju, Wei Yu Chen, Sher Singh, Chung Min Liao

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

The purpose of this paper was to examine trade-offs between elimination and detoxification in rainbow trout and three common bivalve molluscs (clam, oyster, and scallop) exposed to cadmium (Cd), copper (Cu), and zinc (Zn) based on recent reported experimental data. We incorporated metal influx threshold with subcellular partitioning to estimate rate constants of detoxification (k d) and elimination (k 2). We found that the relationships between k 2 and k d were negative for rainbow trout and positive for bivalve molluscs. However, the relationships between k d and % metal in metabolically detoxified pool were found positive for rainbow trout and negative for bivalve molluscs. Our results also indicated that rainbow trout had higher accumulation (∼60-90%) in metabolically active pool when exposed to essential metals of Cu and Zn and had only 10-50% accumulation in response to non-essential metal of Cd. Based on a cluster analysis, this study indicated that similarity of physiological regulations among study species was found between Cd and Zn. Our study suggested that detoxification can be predicted by an elimination-detoxification scheme with the known elimination rate constant. We concluded that quantification of trade-offs between subcellular partitioning and detoxification provides valuable insights into the ecotoxicology of aquatic organisms and enhances our understanding of the subcellular biology of trace metals.

Original languageEnglish
Pages (from-to)1048-1056
Number of pages9
JournalChemosphere
Volume85
Issue number6
DOIs
Publication statusPublished - 2011 Oct 1

Keywords

  • Bivalve mollusc
  • Detoxification
  • Elimination
  • Metal stressor
  • Rainbow trout
  • Subcellular partitioning

ASJC Scopus subject areas

  • Environmental Engineering
  • Environmental Chemistry
  • Chemistry(all)
  • Pollution
  • Health, Toxicology and Mutagenesis

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