Toward integrated plasmonics for biosensing

Chii Wann Lin, Nan Fu Chiu, Jhen Gang Huang, Chih Kung Lee

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    Nano/microtechnologies have been used to fabricate several novel surface plasmon resonant (SPR) devices for the applications in biomolecular sensing. Bioplasmonics have been used to describe the use of biomolecules as a part of the plasmon oscillating system to actively interact with nano/micro structure. We have reported a novel design of alternative dielectric layers to enhance the SPR signal quality and modulate its resonant position. Admittance loci method of thin film design has been used in the design of such a device. The revisit of Maxwell equations also leads to the development of a novel SPR device, which is based on the lateral propagation of surface plasmon wave along the metal-dielectric surface. For the realization of a hand-held SPR system, we have also developed three SPR waveguide sensors. A lateral flow microfluidic channel based on nitrocellulose membrane has been integrated with SPR waveguide sensor and achieved dynamic detection. An integrated SPR device, which couples OLED light source with nano grating structure and top sensing layer, has been tested and found anglar dependence emission. The extended applications of these fundamental principles and novel devices, especially for drug screening and disease diagnosis will be discussed during presentation.

    Original languageEnglish
    Title of host publicationProceedings of the 5th International Conference on Nanochannels, Microchannels and Minichannels, ICNMM2007
    Pages1053-1059
    Number of pages7
    DOIs
    Publication statusPublished - 2007 Dec 21
    Event5th International Conference on Nanochannels, Microchannels and Minichannels, ICNMM2007 - Puebla, Mexico
    Duration: 2007 Jun 182007 Jun 20

    Publication series

    NameProceedings of the 5th International Conference on Nanochannels, Microchannels and Minichannels, ICNMM2007

    Other

    Other5th International Conference on Nanochannels, Microchannels and Minichannels, ICNMM2007
    Country/TerritoryMexico
    CityPuebla
    Period2007/06/182007/06/20

    ASJC Scopus subject areas

    • Mechanical Engineering
    • Physics and Astronomy(all)

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