Toward carboxylate group functionalized A4, A2B 2, A3B oxaporphyrins and zinc complex of oxaporphyrins

Ram Ambre, Chien Yi Yu, Sandeep B. Mane, Ching-Fa Yao, Chen Hsiung Hung

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Series of new oxaporphyrins were isolated from the reaction of furan-1,4-diol, pyrrole, and an aldehyde under Lindsey's conditions, which gives easy access to ester group functionalized oxaporphyrins. The ester substituents can be readily hydrolyzed to terminal carboxylic acid in the presence of KOH. The Zn(II) oxaporphyrins have been synthesized from the reaction of free base with ZnCl2 and fully characterized by variable temperature NMR, 2D NMR, and single crystal X-ray diffraction studies.

Original languageEnglish
Pages (from-to)4680-4688
Number of pages9
JournalTetrahedron
Volume67
Issue number25
DOIs
Publication statusPublished - 2011 Jun 24

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Keywords

  • Core-Modified Porphyrin
  • Oxaporphyrin
  • Porphyrin Synthesis
  • X-ray structure
  • Zinc Porphyrin

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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