Abstract
Series of new oxaporphyrins were isolated from the reaction of furan-1,4-diol, pyrrole, and an aldehyde under Lindsey's conditions, which gives easy access to ester group functionalized oxaporphyrins. The ester substituents can be readily hydrolyzed to terminal carboxylic acid in the presence of KOH. The Zn(II) oxaporphyrins have been synthesized from the reaction of free base with ZnCl2 and fully characterized by variable temperature NMR, 2D NMR, and single crystal X-ray diffraction studies.
Original language | English |
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Pages (from-to) | 4680-4688 |
Number of pages | 9 |
Journal | Tetrahedron |
Volume | 67 |
Issue number | 25 |
DOIs | |
Publication status | Published - 2011 Jun 24 |
Keywords
- Core-Modified Porphyrin
- Oxaporphyrin
- Porphyrin Synthesis
- X-ray structure
- Zinc Porphyrin
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry