TY - JOUR
T1 - Theory for the bending rigidity of protein-coated lipid membranes
AU - Chen, C. M.
N1 - Funding Information:
We thank P.G. Higgs, F.C. MacKintosh, and P.D. Olmsted for stimulating interactions. This work was supported by National Science Council of ROC under grant number NSC 89-2112-M-003-001.
PY - 2000/6/15
Y1 - 2000/6/15
N2 - We study the bending rigidity of protein-coated lipid bilayer membranes by a continuum Landau theory. For up-down symmetric membrane proteins, the bending rigidity (κ) of the membrane is found to increase linearly with protein fraction (φ) and coupling strength (λ) due to the coupling between membrane curvature and local protein fraction. We estimate the coupling strength as λ ∝ κap2/al2, where ap and al are the lateral sizes of proteins and lipids, respectively. Estimated values of λ/κ are given for various combinations of membrane proteins and lipids. We show that the presence of membrane proteins leads to thinning of the effective membrane thickness and reduces the mean layer spacing of a stack of bilayers.
AB - We study the bending rigidity of protein-coated lipid bilayer membranes by a continuum Landau theory. For up-down symmetric membrane proteins, the bending rigidity (κ) of the membrane is found to increase linearly with protein fraction (φ) and coupling strength (λ) due to the coupling between membrane curvature and local protein fraction. We estimate the coupling strength as λ ∝ κap2/al2, where ap and al are the lateral sizes of proteins and lipids, respectively. Estimated values of λ/κ are given for various combinations of membrane proteins and lipids. We show that the presence of membrane proteins leads to thinning of the effective membrane thickness and reduces the mean layer spacing of a stack of bilayers.
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U2 - 10.1016/S0378-4371(00)00037-6
DO - 10.1016/S0378-4371(00)00037-6
M3 - Conference article
AN - SCOPUS:0033686372
SN - 0378-4371
VL - 281
SP - 41
EP - 50
JO - Physica A: Statistical Mechanics and its Applications
JF - Physica A: Statistical Mechanics and its Applications
IS - 1
T2 - 5th Taiwan International Symposium on Statistical Physics (StatPhys-Taiwan-1999)
Y2 - 9 August 1999 through 12 August 1999
ER -