Theory for the bending rigidity of protein-coated lipid membranes

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Abstract

We study the bending rigidity of protein-coated lipid bilayer membranes by a continuum Landau theory. For up-down symmetric membrane proteins, the bending rigidity (κ) of the membrane is found to increase linearly with protein fraction (φ) and coupling strength (λ) due to the coupling between membrane curvature and local protein fraction. We estimate the coupling strength as λ ∝ κap2/al2, where ap and al are the lateral sizes of proteins and lipids, respectively. Estimated values of λ/κ are given for various combinations of membrane proteins and lipids. We show that the presence of membrane proteins leads to thinning of the effective membrane thickness and reduces the mean layer spacing of a stack of bilayers.

Original languageEnglish
Pages (from-to)41-50
Number of pages10
JournalPhysica A: Statistical Mechanics and its Applications
Volume281
Issue number1
DOIs
Publication statusPublished - 2000 Jun 15
Event5th Taiwan International Symposium on Statistical Physics (StatPhys-Taiwan-1999) - Taipei, Taiwan
Duration: 1999 Aug 91999 Aug 12

ASJC Scopus subject areas

  • Statistics and Probability
  • Condensed Matter Physics

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