The reaction of the highly functionalized copper reagents RCu(CN)ZnI.BF3 with aldehydes

Ming Chang P. Yeh, Paul Knochel, Leroy E. Santa

Research output: Contribution to journalArticlepeer-review

67 Citations (Scopus)


The new copper reagent RCu(CN)ZnI 2, which may contain important functional groups like the ester, nitrile, enoate or imide group, react in the presence of BF3.OEt2 with aldehydes to afford polyfunctional secondary alcohols in good yields (68-93%).

Original languageEnglish
Pages (from-to)3887-3890
Number of pages4
JournalTetrahedron Letters
Issue number32
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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