Synthesis of Pyrido[2,3-b]indoles via Brønsted-Acid-Promoted Decarboxylative Annulation of 3-Bromopropenals and Ethyl 2-Amino-1H-indole-3-carboxylates

Tang Hao Yang, Veerababurao Kavala, Chun Wei Kuo, Ching Fa Yao

Research output: Contribution to journalArticle

Abstract

The present methodology describes a versatile pathway to furnish α-carbolines from relatively stable 2-amino indole derivatives and 3-bromopropenal. High substrate tolerance, nonmetallic, more efficient, and mild reaction conditions are important aspects.

Original languageEnglish
Pages (from-to)1053-1058
Number of pages6
JournalAsian Journal of Organic Chemistry
Volume9
Issue number7
DOIs
Publication statusPublished - 2020 Jul 1

Keywords

  • 3-bromopropenal
  • Brønsted
  • decarboxylative annulation
  • pyrido[2,3-b]indoles

ASJC Scopus subject areas

  • Organic Chemistry

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