Synthesis of Isoindolo [1,2-b]quinazolin-12(10H)-one by Double Ullman reaction of 2-Iodobenzamides with Copper Cyanide under Microwave Irradiation

Li Chun Lin; Veerababurao Kavala; Sachin Ichake; Ching Fa Yao

doi:10.1002/slct.202302052

Synthesis of Isoindolo [1,2-b]quinazolin-12(10H)-one by Double Ullman reaction of 2-Iodobenzamides with Copper Cyanide under Microwave Irradiation

Li Chun Lin, Veerababurao Kavala, Sachin Ichake, Ching Fa Yao^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

A simple and one-pot method for the synthesis of isoindolo [1,2-b]quinazolin-12(10H)-one derivative via copper-catalyzed tandem reaction of N-(2-bromobenzyl)-2-iodobenzamide as substrate and copper cyanide is developed under microwave irradiation. The procedure is easy and simple and the yields are good to excellent.

Original language	English
Article number	e202302052
Journal	ChemistrySelect
Volume	8
Issue number	33
DOIs	https://doi.org/10.1002/slct.202302052
Publication status	Published - 2023 Sept 5

Keywords

2-Iodobenzamides
Copper catalyst
Isoindolo[1,2-b]quinazolin-12(10H)-ones
One-Pot
Tandem Cyclization

ASJC Scopus subject areas

General Chemistry

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@article{367bb92f76a2463cbb49262133d48e7a,

title = "Synthesis of Isoindolo [1,2-b]quinazolin-12(10H)-one by Double Ullman reaction of 2-Iodobenzamides with Copper Cyanide under Microwave Irradiation",

abstract = "A simple and one-pot method for the synthesis of isoindolo [1,2-b]quinazolin-12(10H)-one derivative via copper-catalyzed tandem reaction of N-(2-bromobenzyl)-2-iodobenzamide as substrate and copper cyanide is developed under microwave irradiation. The procedure is easy and simple and the yields are good to excellent.",

keywords = "2-Iodobenzamides, Copper catalyst, Isoindolo[1,2-b]quinazolin-12(10H)-ones, One-Pot, Tandem Cyclization",

author = "Lin, {Li Chun} and Veerababurao Kavala and Sachin Ichake and Yao, {Ching Fa}",

note = "Publisher Copyright: {\textcopyright} 2023 Wiley-VCH GmbH.",

year = "2023",

month = sep,

day = "5",

doi = "10.1002/slct.202302052",

language = "English",

volume = "8",

journal = "ChemistrySelect",

issn = "2365-6549",

publisher = "Wiley-Blackwell Publishing Ltd",

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TY - JOUR

T1 - Synthesis of Isoindolo [1,2-b]quinazolin-12(10H)-one by Double Ullman reaction of 2-Iodobenzamides with Copper Cyanide under Microwave Irradiation

AU - Lin, Li Chun

AU - Kavala, Veerababurao

AU - Ichake, Sachin

AU - Yao, Ching Fa

PY - 2023/9/5

Y1 - 2023/9/5

N2 - A simple and one-pot method for the synthesis of isoindolo [1,2-b]quinazolin-12(10H)-one derivative via copper-catalyzed tandem reaction of N-(2-bromobenzyl)-2-iodobenzamide as substrate and copper cyanide is developed under microwave irradiation. The procedure is easy and simple and the yields are good to excellent.

AB - A simple and one-pot method for the synthesis of isoindolo [1,2-b]quinazolin-12(10H)-one derivative via copper-catalyzed tandem reaction of N-(2-bromobenzyl)-2-iodobenzamide as substrate and copper cyanide is developed under microwave irradiation. The procedure is easy and simple and the yields are good to excellent.

KW - 2-Iodobenzamides

KW - Copper catalyst

KW - Isoindolo[1,2-b]quinazolin-12(10H)-ones

KW - One-Pot

KW - Tandem Cyclization

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DO - 10.1002/slct.202302052

M3 - Article

AN - SCOPUS:85169573839

SN - 2365-6549

VL - 8

JO - ChemistrySelect

JF - ChemistrySelect

IS - 33

M1 - e202302052

ER -

Synthesis of Isoindolo [1,2-b]quinazolin-12(10H)-one by Double Ullman reaction of 2-Iodobenzamides with Copper Cyanide under Microwave Irradiation

Abstract

Keywords

ASJC Scopus subject areas

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